Background & Aims: Giant cell lesions are relatively common lesions of jaws. A number of cystic, metabolic, osteodystrophic, microbial, tumor and tumor like lesions of the oral cavity are associated with giant cells. Since pathogenesis incidence of lesions, age, gender and their location are vital in the detection of lesions, the aim of this study was to determine the prevalence of oral and facial giant cell lesions within a period of seven years (2004-2011) in the oral and maxillofacial pathology department of dentistry faculty, Tabriz University of Medical Sciences.

Materials & Methods: In this retrospective descriptive study, the records of patients with giant cell lesion diagnosis in the oral and maxillofacial pathology department of Tabriz Dental Faculty during 2004-2011 were studied. Data obtained were analyzed by descriptive statistical methods, comparison test, and SPSS software.

Results: Of 808 studied cases, 98 lesions (12.12%) were giant cell lesions and between them 91.8% were tumor and tumor like lesions. Incidence of the lesions in the fifth and sixth decades was more than other age decades. Most lesions were located in the posterior area of mandible and there was a slightly higher incidence in women than men.

Conclusion: Giant cell lesions are common in oral and jaw location. The most common lesions is peripheral giant cell granuloma.

SOURCE: URMIA MED J 2014: 25(7): 577 ISSN: 1027-3727