Volume 23, Issue 5 (Biomonthly Dec-ـJan 2012)                   Stud Med Sci 2012, 23(5): 549-555 | Back to browse issues page

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Nasiri Rine H, Khanpoor F. Investigate The Relationship Between Cortisol And Testosterone Hormones And Anthropometric Parameters And Liver Enzymes And Blood Glucose In Men. Stud Med Sci. 2012; 23 (5) :549-555
URL: http://umj.umsu.ac.ir/article-1-1499-en.html
Faculty of Medicine, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran , h_nasiri_r@yahoo.com
Abstract:   (12246 Views)

  Received: 23 July, 2012 Accepted: 15 Oct, 2012

  Background & Aims : obesity and particular upper body obesity are important risk factors for diseases. One of the main causes of obesity is hormonal agents . The aim of this study was to investigate the relationship between cortisol and testosterone hormones and anthropometric parameters and liver enzymes and blood glucose in men.

  Materials & Methods : In this study 30 healthy adult males ranging in age from 29 ±7/2 years were randomly chosen and the anthropometric parameters (waist circumference”WC”, waist to hip ratio ”WHR” BMI) blood levels of cortisol and testosterone ˓ SGOT ˓ SGPT ˓ alkaline phosphatase”AP”, glucose ”FBS” were measured.

  Results : cortisol had negative relationship with testosterone (P<0/05)and Positive relationship with waist circumference, WHR ˓ BMI, FBS (P<0/05) and also Positive relationship with alkaline phosphatase (P<0/01) but testosterone had negative relationship with BMI and waist circumference and WHR

  (P<0/05). FBS level was positively correlated with AP (P<0. O5) and BMI, WHR , WC had positive relationship with each other (p<0. 01).

  Mean ± SD cortisol and testosterone levels in overweight subjects and obese were significant higher than normal weight subjects and lower than normal weight subjects (P<0/05),respectively. men with upper body obesity (WHR≥. /9) had significant higher levels of cortisol and lower level of testosterone than men with low WHR (WHR ˂ . /9) (P<0/05). Other variables were not significantly associated with each other.

  Conclusions : The results indicate that cortisol level had a negative correlation with testosterone and elevated serum cortisol and low testosterone were associated with high BMI, upper body fat distribution that are important risk factors for diseases such as Cardiovascular Disease, Diabetes Mellitus, O steoporosis .

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Type of Study: Research | Subject: آناتومی

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