Volume 28, Issue 8 (Monthly_Nov 2017)                   Studies in Medical Sciences 2017, 28(8): 25-32 | Back to browse issues page

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Fatollahzadeh N, Sharifi Y, Gahremani M, Hosseini Jazani N. Anti bacterial effects of nickel nano-particles on biofilm production amounts by B.capacia ATCC 25416. Studies in Medical Sciences 2017; 28 (8) :25-32
URL: http://umj.umsu.ac.ir/article-1-3992-en.html
Urmia University of Medical Sciences , n_jazani@yahoo.com
Abstract:   (4766 Views)
Background & Aims: B.cepacia is one of the causative agents of health care associated infections which have the ability of attachment to different surfaces and biofilm formation is one of the most important virulence factors in pathogenesis of this microorganism. Nanoparticles are key components which are considered for the designing of new antimicrobial agents, no studies have been done on the anti-biofilm effects of Ni-NPs on B.cepacia, so the aim of this study was to evaluate the anti-biofilm effects of different concentrations of Ni-NPs on B.cepacia.
Materials & Methods: Microtiter plate method was used to determine the potential of the B.capacia ATCC 25416 in respect of biofilm production. The amounts of biofilm formation were also measured in the presence of 0.01, 0.1, 0.5 and 1 mg/mL concentrations of Ni-NPs. Statistical analysis was done by one-way ANOVA to determine significant differences between groups.
Results: The study results revealed that B.capacia ATCC 25416 was strong biofilm producer. Biofilm formation significantly decreased in the presence of 1, 0.5 and 0.1 mg/mL of Ni-NPs (p=0.00, 0.00 and 0.008 respectively). Although in the presence of 0.01mg/mL of Ni-NPs decrease in biofilm formation was observed, but it was not statistically significant (P=0.08).
ConclusionThe present study showed the ability of biofilm formation by B.capacia ATCC 25416. On the other hand, the lowering effects of nickel nanoparticles on biofilm formation by this microorganism were observed.
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Type of Study: Research | Subject: میکروبیولوژی

References
1. Mahenthiralingam E, Vandamme P, Campbell ME, Henry DA, Gravelle AM, Wong LT, et al. Infection with Burkholderia cepacia complex genomovars in patients with cystic fibrosis: virulent transmissible strains of genomovar III can replace Burkholderia multivorans. Clin Infect Dis 2001;33(9):1469–75. [PubMed]
2. Huber B, Riedel K, Hentzer M, Heydorn A, Gotschlich A, Givskov M, et al. The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility. Microbiology 2001;147(Pt 9):2517-28. [PubMed]
3. Riedel K, Hentzer M, Geisenberger O, Huber B, Steidle A, Wu H, et al. N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms. Microbiology 2001;147(Pt 12):3249-62. [PubMed]
4. Duan J, Kang J, Han T, Ma Y, Guo Q, Song Y, et al. Report - Prevalence of hospital acquired Burkholderia cepacia infection and its antimicrobial susceptibility in a Chinese hospital. P Pak J Pharm Sci 2017;30(2):551-3. [PubMed]
5. Namasivayam SKR, Preethi M, Bharani A, Robin G, Latha B. Biofilm inhibitory effect of silver nanoparticles coated catheter against Staphylococcus aureus and evaluation of its synergistic effects with antibiotics. Int J Biol Pharm Res 2012;3:259-65. [Google Scholar]
6. Schaefers MM, Liao TL, Boisvert NM, Roux D, Yoder-Himes D, Priebe GP. An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and Pathogenicity. PLoS pathogens 2017;13(1):e1006116. [PubMed]
7. Ferreira AS, Silva IN, Oliveira VH, Cunha R, Moreira LM. Insights into the role of extracellular polysaccharides in Burkholderia adaptation to different environments. Front Cell Infect Microbiol 2011;1:16. [PubMed]
8. Gahremani M SY, Vahedi M, Hosseini Jazani N. Evaluation of the antibacterial effects of nickel nanoparticles on biofilm production of mupirocin resistant isolates of S.aureus. Urmia Med J 2016;26(12):1063-70. [Google Scholar]
9. Habibi N, Jazani NH, Yousefi S. Evaluation of the Antibacterial Effects of Nickel Nanoparticles on Biofilm Production by Streptococcus mutans. J Med Bacteriol 2017;6(1–2):8–14. [Google Scholar]
10. Zaidi S, Misba L, Khan AU. Nano-therapeutics: A revolution in infection control in post antibiotic era. Nanomedicine 2017;13(7):2281–301. [PubMed]
11. Kumar MS, Das AP. Emerging nanotechnology based strategies for diagnosis and therapeutics of urinary tract infections: A review. Adv Colloid Interface Sci 2017; [PubMed]
12. Caraher E, Duff C, Mullen T, Mc Keon S, Murphy P, Callaghan M, et al. Invasion and biofilm formation of Burkholderia dolosa is comparable with Burkholderia cenocepacia and Burkholderia multivorans. J Cyst Fibros 2007;6(1):49–56. [PubMed]
13. Hoseinzadeh E, Makhdoumi P, Taha P, Hossini H, Stelling J, Kamal MA, et al. A Review on Nano-Antimicrobials: Metal Nanoparticles, Methods and Mechanisms. Curr Drug Metab 2017;18(2):120–8. [PubMed]
14. O’Toole GA. Microtiter dish biofilm formation assay. J Vis Exp 2011;(47). [PubMed]
15. Ebrahimi A, Hemati M, Shabanpour Z, Habibian Dehkordi S, Bahadoran S, Lotfalian S, et al. Effects of benzalkonium chloride on planktonic growth and biofilm formation by animal bacterial pathogens. Jundishapur J Microbiol 2015;8(2):e16058. [PubMed]
16. Kamerud KL, Hobbie KA, Anderson KA. Stainless steel leaches nickel and chromium into foods during cooking. J Agric Food Chem 2013;61(39):9495-501. [PubMed]
17. Hoffmann W, Bormann T, Rossi A, Muller B, Schumacher R, Martin I, et al. Rapid prototyped porous nickel-titanium scaffolds as bone substitutes. J Tissue Eng 2014;5:2041731414540674. [PubMed]
18. Pulikkottil VJ CS, Bejoy PU, Femin PK, Paul P, Rishad M. . Corrosion resistance of stainless steel, nickel-titanium, titanium molybdenum alloy, and ion-implanted titanium molybdenum alloy archwires in acidic fluoride-containing artificial saliva: An in vitro study. J Pharm Bioallied Sci 2016:S96-S9. [PubMed]
19. Argueta-Figueroa L M-LR, Scougall-Vilchis RJ, Olea-Mejia OF. . Synthesis, characterization and antibacterial activity of copper, nickel and bimetallic Cu-Ni nanoparticles for potential use in dental materials. Prog Nat Sci 2014;24:321-8. [Google Scholar]
20. I. M. Study of the antibacterial action of metal nanoparticles on clinical strains of gramnegative bacteria. . 2013;8(4). World J Med Sci 2013;8(4). [Google Scholar]
21. Mortazavi H NMM, Nejad Shahrokh Abadi K. Study of the Effect of Silver Nanoparticles on Biofilms Formation by Staphylococcus epidermidis. JRUMS 2015;14(2):125-36. [Google Scholar]

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