Background & Aims: Parkinsonism occurs in all races. Its prevalence in the United States and Western Europe is 2.1 persons per 1,000 populations. Approximately one third of patients have cognitive problems that often doubles after 4 years in 80% of patients with dementia and Parkinson’s disease (PD) occurs in the final stages. The aim of this study was to determine the relationship between visual evoked potential (VEP) and Somatosensory evoked potential (SSEP) findings in patients with Parkinson’s disease with dementia.

Materials & Methods: In a case-control study that performed in neurology department of Tabriz University of medical sciences on patients with PD, the relationship between VEP and SSEP findings in patients with Parkinson's disease with dementia evaluated.

Results: Right VEP denotes AMP in 12 was abnormal and left VEP denote AMP was abnormal in 13 patients. No significant correlation line was found between MMSE score with left and right VEP 100, Left and right VEP AMP, right SSEP P40 and SSEP AMP but there was a significant line correlation between MMSE score with left SESEP and SSEP P40.

Mean right VEP P100 was 104 + 24.18 and mean left VEP P100 was 104.94 + 24 and also, left and right VEP P100 were abnormal in 24(40).

Conclusion: There was no significant difference in mean of P100 Latency in patients with and without functional disorder. No significant difference was observed between patients with Parkinson’s SSEP AMP with and without functional impairment.

SOURCE: URMIA MED J 2014: 25(9): 802 ISSN: 1027-3727