Volume 20, Issue 1 (spring 2009)                   J Urmia Univ Med Sci 2009, 20(1): 50-61 | Back to browse issues page

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A Najafpour , Ph.D, A Sabouri , DVM. INTRODUCING AMNIOTIC MEMBRANE AS A NEW BIOMATERIAL IN CYSTOPLASTY. J Urmia Univ Med Sci. 2009; 20 (1) :50-61
URL: http://umj.umsu.ac.ir/article-1-396-en.html
, a.najafpour@iaurmia.ac.ir
Abstract:   (15306 Views)

 Received: 18 Aug, 2008 Accepted: 4 Feb, 2009


  Background &Aims: Various congenital, malignant and benign acquired diseases may cause disorders in structure and normal function of bladder and therefore making its repair essential. Natural and synthetic alternative materials have been used to increase bladder volume. The aim of the present study was to change an incontinent high pressure low volume bladder into a continent low pressure high volume bladder and therefore providing a precious model for experimental medical studies.

  Materials & Methods : In the an experimental pilot study, using of fresh goat’s amniotic membrane (G.A.M.) as an organic material for bladder grafting in dogs, for the purpose of bladder augmentation were used in six healthy dogs, a piece of cranial wall of bladder, approximately 4-cm2 in diameter was resected and replaced with fresh G.A.M. For the purpose assessment of, microscopic pathologic parameters were studied.

  Results: Pathology findings were: the regeneration of transitional epithelium and proliferation of granulation tissue, No degenerative changes at the junction of the bladder and graft, was seen.

 Conclusion : The results indicate that fresh G.A.M act as a proper scaffold with least disadvantages, for repairing bladder defects in dogs.


  Keywords : Dog, Goat amniotic membrane, Urinary Bladder, Reconstruction.


  Address: Faculty of Veterinary Medicine, Islamic Azad University, Urmia Branch, P.O. Box 969, Urmia 57153, Iran Tel: (+98)9144415097


  Email: a.najafpour@iaurmia.ac.ir


  Source : UMJ 2009: 20(1): 082 ISSN: 1027-3727

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Type of Study: Research | Subject: آناتومی

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