Volume 35, Issue 12 (March 2025)
Studies in Medical Sciences 2025, 35(12): 961-975 |
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Mohammadi T. TELOCYTES, THE ENIGMATIC CELLS OF TISSUE: A NARRATIVE REVIEW. Studies in Medical Sciences 2025; 35 (12) :961-975
URL: http://umj.umsu.ac.ir/article-1-6394-en.html
URL: http://umj.umsu.ac.ir/article-1-6394-en.html
Assiatant professor, Basic Sciences and Pathobiology Department, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran , tymhd@razi.ac.ir
Abstract: (127 Views)
Telocytes are a novel type of mesenchymal cell characterized by a small cell body and distinctive, long extensions called telopods. They are found in many tissues throughout the body. Telopods enable telocytes to communicate with other cells over long distances. Functionally, telocytes play a vital role in maintaining tissue homeostasis, modulating the immune response, promoting tissue repair, and regulating the activity of other cell types. Although definitive markers for identifying telocytes are not yet fully established, they commonly express proteins such as CD34, c-kit, and vimentin. The study of these cells is important for several reasons. Understanding the role of telocytes in various diseases can help develop new treatments. Identifying specific receptors and signaling molecules of telocytes can lead to the development of new drugs to treat diseases. Due to their role in tissue repair, telocytes have significant potential for use in regenerative medicine. However, challenges remain in identifying and understanding the precise function of telocytes in different tissues. The functional diversity of telocytes in different tissues makes their study complex, and the precise molecular mechanisms of telocyte function are not yet fully understood. As a new and exciting research area, telocytes have significant potential to increase our understanding of tissue physiology and diseases.
Type of Study: Review article |
Subject:
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