Volume 31, Issue 6 (September 2020)
Studies in Medical Sciences 2020, 31(6): 476-484 |
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Sadeghi E, Taghizadeh Z, Karami Yar M, Nasimfar A, rasouli J, radvar M. THE EVALUATION OF CERVICAL ADENITIS CHARACTRITES IN CHILDREN ADMITTED TO URMIA MOTAHARI HOSPITAL. Studies in Medical Sciences 2020; 31 (6) :476-484
URL: http://umj.umsu.ac.ir/article-1-5213-en.html
URL: http://umj.umsu.ac.ir/article-1-5213-en.html
Ebrahim Sadeghi 
, Zahra Taghizadeh , Mohammad Karami Yar , Amir Nasimfar * , Javad Rasouli , Mohammad Radvar
, Zahra Taghizadeh , Mohammad Karami Yar , Amir Nasimfar * , Javad Rasouli , Mohammad Radvar
Associate Professor of Pediatric Infectious Diseases, Urmia University of Medical Sciences, Urmia, Iran (Corresponding Author) , ebrahimsadeghiphd@gmail.com
Abstract: (6836 Views)
Background & Aims: Lymphadenitis is a type of inflammatory lymphadenopathy that is caused by the infiltration of inflammatory cells that can occur with or without the formation of abscesses inside the lymph node. Infectious acute lymphadenitis causes are mostly associated with acute viral and bacterial infection. The purpose of this study was to provide a more comprehensive description of the causes and evaluations performed and the effective treatment for patients referred to Shahid Motahari Hospital with cervical infectious lymphadenitis.
Methods & Materials: This retrospective study was performed on 191 children aged 3 months to 14 years admitted to Urmia Shahid Motahari Hospital who were diagnosed with cervical lymphadenitis between 2013 and 2018. Disease records, biological information, type of antibiotic treatment, aggressive procedure, contrast-enhanced CT scan information, treatment duration, and clinical symptoms were collected and a checklist was filled out.
Results: 107 patients (56%) were male and 84 patients (44%) were female. The mean age of patients was 46.65±35.05 months (range 3–168 months). Mean hospitalization duration was 5.54±3.19 days (range 1–22). The most common clinical symptom of the patients referred to the hospital was fever, which was present in 151 patients (79.1%). In 135 patients (70.7%) no aggressive procedure was taken. Abscess drainage was performed in 40 patients (20.9%), mass biopsy in 14 patients (7.3%), and surgery in 2 patients (1%). Thirty-nine patients (20.4%) had cultures that reported negative results in all cases.
Conclusion: The most common diagnosis in children is acute inflammatory lymphadenitis and occurs usually in spring and urban children. It is common in boys under 5 years of age. The most commonly used antibiotic is clindamycin. In cases of abscess, surgical drainage is performed for treatment.
Methods & Materials: This retrospective study was performed on 191 children aged 3 months to 14 years admitted to Urmia Shahid Motahari Hospital who were diagnosed with cervical lymphadenitis between 2013 and 2018. Disease records, biological information, type of antibiotic treatment, aggressive procedure, contrast-enhanced CT scan information, treatment duration, and clinical symptoms were collected and a checklist was filled out.
Results: 107 patients (56%) were male and 84 patients (44%) were female. The mean age of patients was 46.65±35.05 months (range 3–168 months). Mean hospitalization duration was 5.54±3.19 days (range 1–22). The most common clinical symptom of the patients referred to the hospital was fever, which was present in 151 patients (79.1%). In 135 patients (70.7%) no aggressive procedure was taken. Abscess drainage was performed in 40 patients (20.9%), mass biopsy in 14 patients (7.3%), and surgery in 2 patients (1%). Thirty-nine patients (20.4%) had cultures that reported negative results in all cases.
Conclusion: The most common diagnosis in children is acute inflammatory lymphadenitis and occurs usually in spring and urban children. It is common in boys under 5 years of age. The most commonly used antibiotic is clindamycin. In cases of abscess, surgical drainage is performed for treatment.
Type of Study: Research |
Subject:
Pediatric Infectious Disease
References
1. Gallois Y, Cogo H, Debuisson C, Guet-Revillet H, Brehin C, Baladi B, et al. Nontuberculous lymphadenitis in children: What management strategy? Int J Pediatr Otorhinolaryngol 2019;122:196-202. doi: 10.1016/j.ijporl.2019.04.012. [DOI:10.1016/j.ijporl.2019.04.012] [PMID]
2. Spinelli G, Mannelli G, Arcuri F, Venturini E, Chiappini E, Galli L. Surgical treatment for chronic cervical lymphadenitis in children. Experience from a tertiary care paediatric centre on non-tuberculous mycobacterial infections. Int J Pediatr Otorhinolaryngol 2018;108:137-42. doi: 10.1016/j.ijporl.2018.02.042. [DOI:10.1016/j.ijporl.2018.02.042] [PMID]
3. Gautam H, Agrawal SK, Verma SK, Singh UB. Cervical tuberculous lymphadenitis: Clinical profile and diagnostic modalities. Int J Mycobacteriol 2018;7(3):212-6. doi: 10.4103/ijmy.ijmy_99_18. [DOI:10.4103/ijmy.ijmy_99_18] [PMID]
4. Gaddey HL, Riegel AM. Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis. Am Fam Physician 2016;94(11):896-903. [Google Scholar]
5. Uddin MJ, Rahim MA, Hasan MN, Mazumder MK, Haq MM, Rahman MA, et al. Etiological Evaluation of Patients with Lymphadenopathy by Clinical, Histopathological and Microbiological Assessment. Mymensingh Med J 2019;28(4):854-61. [Google Scholar]
6. Weinstock MS, Patel NA, Smith LP. Pediatric Cervical Lymphadenopathy. Pediatr Rev 2018;39(9):433-43. doi: 10.1542/pir.2017-0249. [DOI:10.1542/pir.2017-0249] [PMID]
7. Aljabry MS, Asiri S, Elsafi T, Elyamany G. Generalized lymphadenopathy secondary to isolated extramedullary hematopoiesis as an initial manifestation of primary myelofibrosis. Hematol Rep 2018;10(2):7588. doi: 10.4081/hr.2018.7588. [DOI:10.4081/hr.2018.7588] [PMID] [PMCID]
8. Goroll AH, May LA, Mulley AG. Primary care medicine: office evaluation and management of the adult patient. 2nd Ed. Philadelphia: Lippincott; 1987. [Google Scholar]
9. Riva G, Sensini M, Peradotto F, Scolfaro C, Di Rosa G, Tavormina P. Pediatric neck masses: how clinical and radiological features can drive diagnosis. Eur J Pediatr 2019;178(4):463-71. doi: 10.1007/s00431-018-3305-9. [DOI:10.1007/s00431-018-3305-9] [PMID]
10. Gosche JR, Vick L. Acute, subacute, and chronic cervical lymphadenitis in children. Semin Pediatr Surg 2006; 15(2): 99-106. [DOI:10.1053/j.sempedsurg.2006.02.007] [PMID] [PMCID]
11. Kelly C, Kelly R. Lymphadenopathy in children Pediatr Clin North Am. 1998; 45,875-88 [DOI:10.1016/S0031-3955(05)70051-1] [PMID]
12. Chesney, P. J. Cervical lymphadenopathy. Pediatrics in Review1994; 15: 276-84. [DOI:10.1542/pir.15-7-276] [PMID]
13. Fahim A, Qasim MM, Rosewarne D. Neck as mediastinal extension: Diagnosis of sarcoidosis by core biopsy of cervical lymph nodes. Clin Respir J 2020; 14(1):16-20. [DOI:10.1111/crj.13094] [PMID]
14. Jayapal N, Ram SKM, Murthy VS, Basheer SA, Shamsuddin SV, Khan AB. Differentiation Between Benign and Metastatic Cervical Lymph Nodes Using Ultrasound. J Pharm Bioallied Sci 2019;11(Suppl 2):S338-S346. doi: 10.4103/JPBS.JPBS_26_19. [DOI:10.4103/JPBS.JPBS_26_19] [PMID] [PMCID]
15. Moskovitz JM, Moy J, Seiwert TY, Ferris RL. Immunotherapy for Head and Neck Squamous Cell Carcinoma: A Review of Current and Emerging Therapeutic Options. Oncologist 2017;22(6):680-93. [DOI:10.1634/theoncologist.2016-0318] [PMID] [PMCID]
16. Koh J, Walsh P, D'Costa I, Bhatti O. Head and neck squamous cell carcinoma survivorship care. Aust J Gen Pract 2019;48(12):846-8. doi: 10.31128/AJGP-08-19-5032. [DOI:10.31128/AJGP-08-19-5032] [PMID]
17. Neff L, Newland JG, Sykes KJ, Selvarangan R, Wei JL. Microbiology and antimicrobial treatment of pediatric cervical lymphadenitis requiring surgical intervention. Nt J Pediatr Otorhinolaryngol 2013; 77(5): 817-20. [DOI:10.1016/j.ijporl.2013.02.018] [PMID]
18. Georget E, Gauthier A, Brugel L, Verlhac S, Remus N, Epaud R, et al. Acute cervical lymphadenitis and infections of the retropharyngeal and parapharyngeal spaces in children. BMC Ear, Nose and Throat Disorders 2008; 14(1): 8. [DOI:10.1186/1472-6815-14-8] [PMID] [PMCID]
19. Scott CA, Atkinson SH, Sodha A, Tate C, Sadiq J, Lakhoo K, et al. Management of lymphadenitis due to non-tuberculous mycobacterial infection in children. Pediatr Surg Int 2012; 28: 461-6. [DOI:10.1007/s00383-012-3068-8] [PMID]
20. Niedzielska G, Kotowski M, Niedzielski A, Dybiec E, Wieczorek P. Cervical lymphadenopathy in children-incidence and diagnostic management. Int J Pediatr Otorhinolaryngol 2007; 71(1): 51-6. [DOI:10.1016/j.ijporl.2006.08.024] [PMID]
21. Worley ML, Seif JM, Whigham AS, Mims JW, Shetty AK, Evans AK. Suppurative cervical lymphadenitis in infancy: microbiology and sociology. Clin Pediatr (Phila) 2015; 54(7): 629-34. [DOI:10.1177/0009922815584548] [PMID]
22. Tortoli E. Epidemiology of cervico-facial pediatric lymphadenitis as a result of nontuberculous mycobacteria. International Journal of Mycobacteriology 2012; 1: 165 -9. [DOI:10.1016/j.ijmyco.2012.10.008] [PMID]
23. Zimmermann P, Tebruegge M, Curtis N, Ritz N. The management of non-tuberculous cervicofacial lymphadenitis in children: A systematic review and meta-analysis. Journal of Infection 2015; 7,1: 9-18. [DOI:10.1016/j.jinf.2015.02.010] [PMID]
24. Kimia AA, Rudloe TF, Aprahamian N, McNamara J, Roberson D, Landschaft A, , et al. Predictors of a drainable suppurative adenitis among children presenting with cervical adenopathy. Am J Emerg Med 2019;37(1):109-13. [DOI:10.1016/j.ajem.2018.05.004] [PMID]
25. Golriz F, Bisset GS, D'Amico B, Cruz AT, Alade KH, Zhang W, et al. A clinical decision rule for the use of ultrasound in children presenting with acute inflammatory neck masses. Pediatr Radiol 2017;47(4):422-8. [DOI:10.1007/s00247-016-3774-9] [PMID]
26. Safont M, Angelakis E, Richet H, Lepidi H, Fournier PE, Drancourt M, et al. Bacterial lymphadenitis at a major referral hospital in France from 2008 to 2012. J Clin Microbiol 2008; 52(4): 1161-7. [DOI:10.1128/JCM.03491-13] [PMID] [PMCID]
27. Zielnik J, Pysz K. Acute lymphadenitis of the neck in children. Otolaryngol Pol 2005; 59(2): 209-14. [Google Scholar]
28. Matos R, Martins S, Marques P, Santos M. Unilateral acute cervical lymphadenitis in children: can we predict the need for surgery? Int J Pediatr Otorhinolaryngol 2019;127:109655. [DOI:10.1016/j.ijporl.2019.109655] [PMID]
29. Kwon M, Seo JH, Cho KJ, Won SJ, Woo SH, Kim JP, et al. Suggested Protocol for Managing Acute Suppurative Cervical Lymphadenitis in Children to Reduce Unnecessary Surgical Interventions. Ann Otol Rhinol Laryngol 2016;125(12):953-8. [DOI:10.1177/0003489416665194] [PMID]
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