Volume 35, Issue 1 (3-2024)                   Studies in Medical Sciences 2024, 35(1): 51-59 | Back to browse issues page

Ethics code: IR.GUMS.REC.1396.530


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Joukar F, Hosseini Basti R S, Hosseini Basti F S, Mosafer F, Hosseini Basti H S, Hedayatzadeh Z et al . ASSESSMENT OF PATIENTS WITH NON-VARICEAL UPPER GASTROINTESTINAL BLEEDING USING AIMS65 SCORE. Studies in Medical Sciences 2024; 35 (1) :51-59
URL: http://umj.umsu.ac.ir/article-1-6033-en.html
Professor of Gastrointestinal and Liver Diseases in Adults, Gilan Gastrointestinal and Liver Diseases Research Center, Gilan University of Medical Sciences, Rasht, Iran (Corresponding Author) , Drafshinshafaghi@gmail.com
Abstract:   (1566 Views)
Background & Aims: The upper gastrointestinal bleeding (GIB) is a common emergency in hospital admission among patients with internal diseases. The aim of this study was to investigate the outcomes of patients with non-variceal upper GIB‚ using the AIMS65 index in the Razi hospital in Rasht, 2018-2019.
Materials & Methods: In this cross-sectional study, 112 patients with GIB, referred to Razi Hospital in Rasht between 2017-2018 were selected using convenient sampling method and included in the study. The AIMS65 score was used to check GIB. In this score, some risk factors including albumin, INR, and hemoglobin levels and systolic blood pressure of both hands, consciousness based on Glasgow criteria, and age were documented. The score of the patients were calculated based on how many risk factors they had from 0 to 5. Based on this, patients are classified into two groups of high-risk or emergency (with a score of >2) and low-risk or non-emergency (with a score of < 2) and then endoscopy is performed on them.
Results: Based on AIMS65 score, 73.2% of the patients had scores below 2 and classified in the non-emergency group, and the rest had scores higher than 2 and classified in the emergency group. The results showed that there was a statistically significant difference between the risk of in-hospital mortality, rebleeding, and the mortality status of the patients 3 months after the first referral. (p<0.05).
Conclusion: In this study, we concluded that AIMS65 score is effective in predicting in-hospital mortality and recurrent hemorrhage and its prognosis. However, it cannot be a suitable criterion in determining need, time, and endoscopic interventions for ICU hospitalization.
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Type of Study: Research | Subject: گوارش و کبد

References
1. Network SIG. Management of Acute Upper and Lower Gastrointestinal Bleeding: A National Clinical Guideline. Edinburgh. Sign 2008. [URL]
2. Kohn A, Ancona C, Belleudi V, Davoli M, Giglio L, Fusco D, et al. The impact of endoscopy and specialist care on 30-day mortality among patients with acute non-variceal upper gastrointestinal hemorrhage: an Italian population-based study. Digestive Liver Dis 2010;42(9): 629-34. https: //doi.org/10.1016/j.dld.2010.03.012 [DOI:10.1016/j.dld.2010.03.012] [PMID]
3. Yousefinejad V, Darvishi N, Taheri A, Babahajian A, Ghafory H, Manoochehri F, et al. Evaluation of demographic and behavioral characteristics of patients using non-steroidal, anti-inflammatory and combinatory drugs related with Upper Gastrointestinal Bleeding. Sci J Kurdistan Univ Med Sci 2017;22(4): 18-26. [Google Scholar]
4. Gado A, Ebeid B, Abdelmohsen A, Axon A. The management of low-risk acute upper gastrointestinal haemorrhage in the community in Egypt. Alexandria J Med 2013;49(3): 195-8. https: //doi.org/10.1016/j.ajme.2012.10.006 [DOI:10.1016/j.ajme.2012.10.006]
5. Habibi Kootenaei N, Shayesteh AA, Parsi A, Seyedian SS, Latifi M, Rezaei MJ. Epidemiologic study of gastrointestinal bleeding in admitted patients at Imam khomeini hospital in 2018-2019. Jundishapur Sci Med J 2020;19(1): 47-52. [Google Scholar]
6. Ebrahimi N FA. Approach and treatment of patients with overt UGIB. J Med Council Iran 2016;33(4): 356-61.
7. Lahiff C, Shields W, Cretu I, Mahmud N, McKiernan S, Norris S, et al. Upper gastrointestinal bleeding: predictors of risk in a mixed patient group including variceal and nonvariceal haemorrhage. Eur J Gastroenterol Hepatol 2012;24(2): 149-54. https: //doi.org/10.1097/MEG.0b013e32834e37d6 [DOI:10.1097/MEG.0b013e32834e37d6] [PMID]
8. Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for uppergastrointestinal haemorrhage. Lancet 2000;356(9238): 1318-21. https: //doi.org/10.1016/S0140-6736(00)02816-6 [DOI:10.1016/S0140-6736(00)02816-6] [PMID]
9. Stanley A, Ashley D, Dalton H, Mowat C, Gaya D, Thompson E, et al. Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. Lancet 2009;373(9657): 42-7. https: //doi.org/10.1016/S0140-6736(08)61769-9 [DOI:10.1016/S0140-6736(08)61769-9] [PMID]
10. Park SW, Song YW, Tak DH, Ahn BM, Kang SH, Moon HS, et al. The AIMS65 score is a useful predictor of mortality in patients with nonvariceal upper gastrointestinal bleeding: urgent endoscopy in patients with high AIMS65 scores. Clin Endoscopy 2015;48(6): 522-7. https: //doi.org/10.5946/ce.2015.48.6.522 [DOI:10.5946/ce.2015.48.6.522] [PMID] []
11. Thandassery RB, Sharma M, John AK, Al-Ejji KM, Wani H, Sultan K, et al. Clinical application of AIMS65 scores to predict outcomes in patients with upper gastrointestinal hemorrhage. Clin Endoscopy 2015;48(5): 380-4. https: //doi.org/10.5946/ce.2015.48.5.380 [DOI:10.5946/ce.2015.48.5.380] [PMID] []
12. Gaduputi V, Abdulsamad M, Tariq H, Rafeeq A, Abbas N, Kumbum K, et al. Prognostic value of AIMS65 score in cirrhotic patients with upper gastrointestinal bleeding. Gastroenterol Res Pract 2014;2014. https: //doi.org/10.1155/2014/787256 [DOI:10.1155/2014/787256] [PMID] []
13. Hyett BH, Abougergi MS, Charpentier JP, Kumar NL, Brozovic S, Claggett BL, et al. The AIMS65 score compared with the Glasgow-Blatchford score in predicting outcomes in upper GI bleeding. Gastrointestinal Endoscopy 2013;77(4): 551-7. https: //doi.org/10.1016/j.gie.2012.11.022 [DOI:10.1016/j.gie.2012.11.022] [PMID]
14. Jung SH, Oh JH, Lee HY, Jeong JW, Go SE, You CR, et al. Is the AIMS65 score useful in predicting outcomes in peptic ulcer bleeding? World journal of gastroenterology: WJG. 2014;20(7): 1846. https: //doi.org/10.3748/wjg.v20.i7.1846 [DOI:10.3748/wjg.v20.i7.1846] [PMID] []
15. Saltzman JR, Tabak YP, Hyett BH, Sun X, Travis AC, Johannes RS. A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding. Gastrointestinal Endoscopy 2011;74(6): 1215-24. https: //doi.org/10.1016/j.gie.2011.06.024 [DOI:10.1016/j.gie.2011.06.024] [PMID]
16. Soleymanian T, Ghaziani Z. Charlson Comorbidity Index as a Strong Predictor of Mortality in Patients with Chronic Hemodialysis. Umsha. 2018;25: 151-8. https: //doi.org/10.21859/ajcm.25.3.151 [DOI:10.21859/ajcm.25.3.151]
17. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40(5): 373-83. https: //doi.org/10.1016/0021-9681(87)90171-8 [DOI:10.1016/0021-9681(87)90171-8] [PMID]
18. Momenyan S, Kabiri F, Gholamichaboki B, Arjmand A, Heidarifar R. Reliability and predictive validity of outcome at discharge of Glascow coma scale in an intensive care unit population. Koomesh 2017;19(1): 129-34. [Google Scholar]
19. Gado AS, Ebeid BA, Abdelmohsen AM, Axon AT. Clinical outcome of acute upper gastrointestinal hemorrhage among patients admitted to a government hospital in Egypt. Saudi J Gastroenterol 2012;18(1): 34. https: //doi.org/10.4103/1319-3767.91737 [DOI:10.4103/1319-3767.91737] [PMID] []
20. Farrell JJ, Friedman LS. Gastrointestinal bleeding in older people. Gastroenterol Clinics N Am 2000;29(1): 1-36. https: //doi.org/10.1016/S0889-8553(05)70106-0 [DOI:10.1016/S0889-8553(05)70106-0] [PMID]
21. Palmer AJ, Moroni F, Mcleish S, Campbell G, Bardgett J, Round J, et al. Risk assessment in acute non-variceal upper GI bleeding: the AIMS65 score in comparison with the Glasgow-Blatchford score in a Scottish population. Front Gastroenterol 2016;7(2): 90-6. https: //doi.org/10.1136/flgastro-2015-100594 [DOI:10.1136/flgastro-2015-100594] [PMID] []
22. Gu L, Xu F, Yuan J. Comparison of AIMS65, Glasgow-Blatchford and Rockall scoring approaches in predicting the risk of in-hospital death among emergency hospitalized patients with upper gastrointestinal bleeding: a retrospective observational study in Nanjing, China. BMC Gastroenterol 2018;18(1): 1-8. https: //doi.org/10.1186/s12876-018-0828-5 [DOI:10.1186/s12876-018-0828-5] [PMID] []
23. Zhong M, Chen WJ, Lu XY, Qian J, Zhu CQ. Comparison of three scoring systems in predicting clinical outcomes in patients with acute upper gastrointestinal bleeding: a prospective observational study. J Digestive Dis 2016;17(12): 820-8. https: //doi.org/10.1111/1751-2980.12433 [DOI:10.1111/1751-2980.12433] [PMID]
24. Jeong N, Kim KS, Jung YS, Kim T, Shin SM. Delayed endoscopy is associated with increased mortality in upper gastrointestinal hemorrhage. Am J Emergency Med 2019;37(2): 277-80. https: //doi.org/10.1016/j.ajem.2018.05.049 [DOI:10.1016/j.ajem.2018.05.049] [PMID]
25. Choe JW, Kim SY, Hyun JJ, Jung SW, Jung YK, Koo JS, et al. Is the AIMS 65 score useful in prepdicting clinical outcomes in Korean patients with variceal and nonvariceal upper gastrointestinal bleeding? Gut Liver 2017;11(6): 813. https: //doi.org/10.5009/gnl16607 [DOI:10.5009/gnl16607] [PMID] []
26. Chang A, Ouejiaraphant C, Akarapatima K, Rattanasupa A, Prachayakul V. Prospective comparison of the AIMS65 score, Glasgow-Blatchford score, and Rockall score for predicting clinical outcomes in patients with variceal and nonvariceal upper gastrointestinal bleeding. Clin Endoscopy 2021;54(2): 211-21. https: //doi.org/10.5946/ce.2020.068 [DOI:10.5946/ce.2020.068] [PMID] []
27. Kim MS, Choi J, Shin WC. AIMS65 scoring system is comparable to Glasgow-Blatchford score or Rockall score for prediction of clinical outcomes for non-variceal upper gastrointestinal bleeding. BMC Gastroenterology 2019;19(1): 1-8. https: //doi.org/10.1186/s12876-019-1051-8 [DOI:10.1186/s12876-019-1051-8] [PMID] []

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