Received: 9 Jul, 2015 Accepted: 14 Sep, 2015

Abstract

Background & Aims: Dehydration can lead to exacerbation of Jaundice and renal failure (ARF). It may also be associated between renal failure and jaundice. One of the common causes of ARF and jaundice is inadequate breastfeeding. The purpose of this study was to evaluate the relationship between dehydration resulting from inadequate Breastfeeding and Clinical course of jaundice and prenatal azotemia in newborns.

Materials & Methods: This descriptive-analytic study was conducted during the period 2006-2012 on 282 hospitalized infant with Jaundice. The study population included all infants with jaundice admitted to the neonatal intensive care unit of Ghaem hospital that renal function tests were performed on them. Experimental group (141 infant) include of neonates with serum creatinine level >1.2 mg/dl and the serum urea level > 40 mg/dl and lower than this values were in the control group (141 infant). T-Test, Mann-Whitney, chi-square and Roc curve were used to analyze the data.

Results: Fourteen percent of neonatal jaundice had ARF. The most common symptoms at presentation after Jaundice in case group was Hyperthermia, weight loss, irritability, poor feeding and in control group was Jaundice. The weight loss>%10 properly diagnosed more than 86% of case group and 78% of neonates in control group. The weight loss > 7%, properly diagnosed over 75% of neonates with ARF and 80% healthy infants.

Conclusion: Neonatal jaundice must be monitored weight loss and its effects.Hyperbilirubinemia infants with restless or hyperthermia must be evaluated from weight loss. Evaluation of renal failure is necessary in weight loss >%7.

SOURCE: URMIA MED J 2015: 26(7): 624 ISSN: 1027-3727