Volume 34, Issue 10 (12-2023)                   Studies in Medical Sciences 2023, 34(10): 643-650 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Houshmand H, Ghaemi R, Alipour M. EPIDEMIOLOGICAL STUDY OF CLINICAL FINDINGS AND OUTCOME OF HOSPITALIZED INFANTS AND CHILDREN WITH FOOD ALLERGY. Studies in Medical Sciences 2023; 34 (10) :643-650
URL: http://umj.umsu.ac.ir/article-1-5993-en.html
Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran. , Dr.reza.ghaemi@gmail.com
Abstract:   (1350 Views)
Introduction:Food allergies or additive reactions occur as an adverse immune response to food allergens. Food allergies vary with age, local food, and many other factors. The purpose of this study was to determine the causes, types, demographic, clinical, and laboratory characteristics and outcomes of infants and children hospitalized in Motahari Hospital with a diagnosis of food allergy in 2009-2019.
Materials and methods: In this retrospective cross-sectional descriptive study, infants and children admitted to Motahari Hospital in Urmia between 2019 and 2019 were examined due to food allergies. Information such as age, gender, location, clinical symptoms, etc. were extracted from the files of these patients and then analyzed.
Findings: The average age of the patients in this study was 9.43 months. Boys constituted 57.1% of the studied population. Family history of food allergy was positive in only 2.6% of patients. The prevalence in different seasons was winter (31.2%), summer (28.6%), autumn (26%) and spring (14.3%). The prevalence of allergenic foods was cow's milk (85.7%) and eggs (2.6%). Non-IgE sensitivity was 79.2% and IgE sensitivity was 20.8%. Clinical symptoms in children and infants with food allergy included enterocolitis (77.9%), urticaria and angioedema (11.7%), urticaria (5.2%) and angioedema (5.2%).
Conclusion: The results of this study showed that boys and people living in the city constitute a higher percentage of the studied society. Winter was also the most common season. The most common allergen was cow's milk, and most patients had non-IgE-related allergies. The most common clinical symptoms in patients were enterocolitis, urticaria, and skin rash. Mortality was not observed among patients.
 
Full-Text [PDF 364 kb]   (697 Downloads)    
Type of Study: Research | Subject: کودکان (عمومی)

References
1. Sicherer SH. IgE-and Non-IgE-Mediated Food Allergy. Eosinophilic Esophagitis 2012:219-38. [DOI:10.1007/978-1-60761-515-6_16]
2. Chehade M. IgE and non-IgE-mediated food allergy: treatment in 2007. Curr Opin Allergy Clin Immunol 2007;7(3):264-8. [DOI:10.1097/ACI.0b013e32814a5607] [PMID]
3. Savage JH, Matsui EC, Skripak JM, Wood RA. The natural history of egg allergy. J Allergy Clin Immunol 2007;120(6):1413-7. [DOI:10.1016/j.jaci.2007.09.040] [PMID]
4. Bahna SL. Clinical expressions of food allergy. Ann Allergy Asthma Immunol 2003;90(6):41-4. [DOI:10.1016/S1081-1206(10)61659-6] [PMID]
5. Gupta RS, Warren CM, Smith BM, Jiang J, Blumenstock JA, Davis MM, et al. Prevalence and severity of food allergies among US adults. JAMA Netw Open 2019;2(1):e185630-e. [DOI:10.1001/jamanetworkopen.2018.5630] [PMID] []
6. Metcalfe DD, Sampson HA, Simon RA. Food allergy: adverse reactions to foods and food additives: John Wiley & Sons; 2011. [Google Scholar]
7. Waserman S, Watson W. Food allergy. Allergy Asthma Clin Immunol 2011;7:1-7. [DOI:10.1186/1710-1492-7-S1-S7] [PMID] []
8. Sicherer SH, Munoz-Furlong A, Murphy R, Wood RA, Sampson HA. Symposium: pediatric food allergy. Pediatrics 2003;111(Supplement_3):1591-4. [DOI:10.1542/peds.111.S3.1591]
9. Johansson S, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, et al. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol 2004;113(5):832-6. [DOI:10.1016/j.jaci.2003.12.591] [PMID]
10. Sicherer SH, Sampson HA. Peanut allergy: emerging concepts and approaches for an apparent epidemic. J Allergy Clin Immunol 2007;120(3):491-503. [DOI:10.1016/j.jaci.2007.07.015] [PMID]
11. Mukoyama T, Nishima S, Arita M, Ito S, Urisu A, Ebisawa M, et al. Guidelines for diagnosis and management of pediatric food allergy in Japan. Allergol Int 2007;56(4):349-61. [DOI:10.2332/allergolint.R-06-138] [PMID]
12. Pourpak Z, Farhoudi A, Arshi S, Movahedi M, Gharegozlou M, Yazdani F, et al. Common food allergens in Iranian children. Iran J Med Sci 2015;28(1):17-22. [Google Scholar]
13. Guler N, Cokugras F, Sapan N, Selimoglu A, Turktas I, Cokugras H, et al. Diagnosis and management of cow's milk protein allergy in Turkey: Region-specific recommendations by an expert-panel. Allergol Immunopathol 2020;48(2):202-10. [DOI:10.1016/j.aller.2019.05.004] [PMID]
14. Oshnooi S, Khalkhali H, Karamiyar M. Association Between Duration of Breast Feeding and Asthma at Children Between at Age 2-8 Years. Stud Med Sci 2012;23(1):1-6. [Google Scholar]
15. Bawany F, Beck LA, Järvinen KM. Halting the march: primary prevention of atopic dermatitis and food allergies. J Allergy Clin Immunol Pract 2020;8(3):860-75. [DOI:10.1016/j.jaip.2019.12.005] [PMID] []
16. Sikorska-Szaflik H, Sozańska B. Primary prevention of food allergy-Environmental protection beyond diet. Nutrients 2021;13(6):2025. [DOI:10.3390/nu13062025] [PMID] []
17. Rona RJ, Keil T, Summers C, Gislason D, Zuidmeer L, Sodergren E, et al. The prevalence of food allergy: a meta-analysis. J Allergy Clin Immunol 2007;120(3):638-46. [DOI:10.1016/j.jaci.2007.05.026] [PMID]
18. Ahanchian H, Jafari S, Behmanesh F, Haghi NM, Nakhaei AA, Kiani MA, et al. Epidemiological survey of pediatric food allergy in Mashhad in Northeast Iran. Electron Physician 2016;8(1):1727. [DOI:10.19082/1727] [PMID] []
19. Leinhas JL, McCaskill CC, Sampson HA. Food allergy challenges: guidelines and implications. J Am Diet Assoc 1987;87(5):604-8. [DOI:10.1016/S0002-8223(21)03162-X] [PMID]
20. Broadbent JB, Sampson HA. Food hypersensitivity and atopic dermatitis. Pediatr Clin North Am 1988;35(5):1115-30. [DOI:10.1016/S0031-3955(16)36552-X] [PMID]
21. Niggemann B, Beyer K, Wahn U. The role of eosinophils and eosinophil cationic protein in monitoring oral challenge tests in children with food-sensitive atopic dermatitis. J Allergy Clin Immunol 1994;94(6):963-71. [DOI:10.1016/0091-6749(94)90114-7] [PMID]
22. Adkinson Jr NF, Bochner BS, Burks AW, Busse WW, Holgate ST, Lemanske RF, et al. Middleton's allergy E-Book: Principles and practice: Elsevier Health Sciences; 2013.
23. Al-Hammadi S, Zoubeidi T, Al-Maskari F. Predictors of childhood food allergy: significance and implications. Asian Pac J Allergy Immunol 2011;29(4):313. [DOI:10.1186/2045-7022-1-S1-P24] []

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Studies in Medical Sciences

Designed & Developed by : Yektaweb