Background &Aims : The effect endurance exercises on hypothalamus are not clear. Exercise is a powerful stimulus for the endocrine system and depends on several factors, ie: duration, intensity and the mode of exercise and training status.

  Materials & Methods : One hundred and thirty volunteered runner men entered to this project but 16 men selected randomly. Excluding from this project were diabeties, cardiovascular and other endocrine problems. Blood samples from runner were obtained in fasting, 30 minutes after running exercise (endurance versus resistance) and 3 hour after resting.

 Results: Serum samples were separated and stored at -40 ⁰C until to be tested. Serum prolactin, testosterone and DHEA-S levels were measured by chemiluminescence automathed systems and results compaired by known standard curve. Statistical analysis carried out by SPss and Paired – Sample Test. All results below 0.05 P value (P < 0.05) considered to be significant. Prolactin and DHEA-S levels increased and testosterone level decreased after 30 minutes running (P < 0.05). But did not change after three hours resting.

 Conclusion: Our investigation show running up to 30 minutes as a endurance condition could increase serum DHEA-S and prolactin levels and decrease in serum testosterone level but they decrease to about fasting condition after three hours resting.

 Address: Urmia University, Faculty of Medicine, Biochemistry, Tel:(+98) 09141415879

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  Source : Urmia Med J 2011: 21(5):451 ISSN: 1027-3727