Volume 36, Issue 1 (4-2025)
Studies in Medical Sciences 2025, 36(1): 84-93 |
Back to browse issues page
Research code: IR.UMSU.REC.1402.033
Ethics code: IR.UMSU.REC.1402.033
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Mohammadi A, Ghaemi S R, Hooshmand H R, Radvar M. Evaluation of frequency and severity of pulmonary hypertension in children with tonsillar hypertrophy who referred. Studies in Medical Sciences 2025; 36 (1) :84-93
URL: http://umj.umsu.ac.ir/article-1-6397-en.html
URL: http://umj.umsu.ac.ir/article-1-6397-en.html
Urmia University of Medical Sciences , ghaemi.m@umsu.ac.ir
Abstract: (73 Views)
Background & Aims: Enlarged adenoids are a common problem in childhood and the most common cause of upper airway obstruction and sleep apnea in children. If untreated, they can cause widespread cardiovascular complications. This study aimed to investigate the prevalence and severity of increased pulmonary artery pressure in children with enlarged adenoids who were referred to the Asthma and Allergy Clinic of Shahid Motahari Hospital in Urmia from 2022 to 2023.
Material and Methods: In this descriptive-analytical study, all children referred to the Asthma and Allergy Clinic of Urmia University of Medical Sciences during 2022 with a diagnosis of enlarged adenoids, confirmed by a doctor using a special mirror or a flexible camera (nasal endoscopy), were evaluated. Information such as age, gender, place of residence, clinical symptoms of the patients (sleep disturbance, frequent colds, etc.), and previous medical history were collected in special data collection forms. The collected data were entered into SPSS version 22 software and statistically analyzed.
Results: The mean age of the 19 patients in the study was 7.4 years, and 63.2% were girls. The mean pulmonary artery pressure was 11.36 mmHg, and the mean ANR among the patients was 0.78. Most patients had severe adenoid enlargement (63.2%). There was no significant difference in pulmonary artery pressure between patients with severe, moderate, and mild adenoid enlargement
(P = 0.53). There was no significant association between ANR and pulmonary artery pressure
(r = 0.02, p = 0.92).
Conclusion: The prevalence of increased pulmonary artery pressure in children with enlarged adenoids was 5.2%, and there was no significant relationship between the severity of enlarged adenoids and pulmonary artery pressure.
Material and Methods: In this descriptive-analytical study, all children referred to the Asthma and Allergy Clinic of Urmia University of Medical Sciences during 2022 with a diagnosis of enlarged adenoids, confirmed by a doctor using a special mirror or a flexible camera (nasal endoscopy), were evaluated. Information such as age, gender, place of residence, clinical symptoms of the patients (sleep disturbance, frequent colds, etc.), and previous medical history were collected in special data collection forms. The collected data were entered into SPSS version 22 software and statistically analyzed.
Results: The mean age of the 19 patients in the study was 7.4 years, and 63.2% were girls. The mean pulmonary artery pressure was 11.36 mmHg, and the mean ANR among the patients was 0.78. Most patients had severe adenoid enlargement (63.2%). There was no significant difference in pulmonary artery pressure between patients with severe, moderate, and mild adenoid enlargement
(P = 0.53). There was no significant association between ANR and pulmonary artery pressure
(r = 0.02, p = 0.92).
Conclusion: The prevalence of increased pulmonary artery pressure in children with enlarged adenoids was 5.2%, and there was no significant relationship between the severity of enlarged adenoids and pulmonary artery pressure.
Type of Study: Research |
Subject:
کودکان (عمومی)
References
1. Bhattacharjee R, Kheirandish-Gozal L, Pillar G, Gozal D. Cardiovascular complications of obstructive sleep apnea syndrome: evidence from children. Prog Cardiovasc Dis 2009;51(5):416-33. [DOI:10.1016/j.pcad.2008.03.002] [PMID]
2. Sie KC, Perkins JA, Clarke WR. Acute right heart failure due to adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 1997;41(1):53-8. [DOI:10.1016/S0165-5876(97)00034-7] [PMID]
3. Tatlıpınar A, Duman D, Uslu C, Egeli E. The effects of obstructive sleep apnea syndrome due to adenotonsillar hypertrophy on the cardiovascular system in children. Turk J Pediatr 2011;53:359-63. [GOOGLE SCHOLAR]
4. Khadivi A, Hari M, Sharifian M, Afzal Aghaei M, Bakhshaei M. Study of the effects of adenotonsillectomy on pulmonary artery pressure using Doppler echocardiography in children. Iran J Ear Nose Throat Laryngol 2008;20:15-20. [URL]
5. Sofer S, Weinhouse E, Tal A, Wanderman KL, Margulis G, Leiberman A, et al. Cor pulmonale due to adenoidal or tonsillar hypertrophy or both in children: noninvasive diagnosis and follow-up. Chest 1988;93(1):119-22. [DOI:10.1378/chest.93.1.119] [PMID]
6. Yilmaz H, Demir I, Uyar Z. Clinical and coronary angiographic characteristics of patients with coronary slow flow. Acta Cardiol 2008;63(5):579-84. [DOI:10.2143/AC.63.5.2033224] [PMID]
7. Granzotto EH, Aquino FV, Flores JA, Neto JFL. Tonsil size as a predictor of cardiac complications in children with sleep‐disordered breathing. Laryngoscope 2010;120(6):1246-51. [DOI:10.1002/lary.20870] [PMID]
8. Wilkinson A, McCormick M, Freeland A, Pickering D. Electrocardiographic signs of pulmonary hypertension in children who snore. Br Med J (Clin Res Ed) 1981;282(6276):1579-81. [DOI:10.1136/bmj.282.6276.1579] [PMID] []
9. Kalra M, Kimball TR, Daniels SR, LeMasters G, Willging PJ, Rutter M, et al. Structural cardiac changes as a predictor of respiratory complications after adenotonsillectomy for obstructive breathing during sleep in children. Medicine 2005;6(3):241-5. [DOI:10.1016/j.sleep.2004.10.004] [PMID]
10. Ramakrishna S, Ingle V, Patel S, Bhat P, Dada J, Shah FA, et al. Reversible cardio-pulmonary changes due to adeno-tonsilar hypertrophy. Int J Pediatr Otorhinolaryngol 2000;55(3):203-6. [DOI:10.1016/S0165-5876(00)00389-X] [PMID]
11. Miman M, Kirazli T, Ozyurek R. Doppler echocardiography in adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 2000;54(1):21-6. [DOI:10.1016/S0165-5876(00)00338-4] [PMID]
12. Görür K, Döven O, Ünal M, Akkuş N, Özcan C. Preoperative and postoperative cardiac and clinical findings of patients with adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 2001;59(1):41-6. [DOI:10.1016/S0165-5876(01)00449-9] [PMID]
13. Foster PJ, Baasanhu J, Alsbirk PH, Munkhbayar D, Uranchimeg D, Johnson GJ. Central corneal thickness and intraocular pressure in a Mongolian population. Ophthalmology 1998;105(6):969-73. [DOI:10.1016/S0161-6420(98)96021-3] [PMID]
14. Jabari M, Ghafari BS, Abavisani K, Sayahmeli R, Ghafari BM, Seyed GG. Subclinical Pulmonary Hypertension in Children with Obstructive Adenotonsillar Hypertrophy. J Pediatr Otorhinolaryngol 2015;82(8):83-87.
15. Marangu D, Jowi C, Aswani J, Wambani S, Nduati R. Prevalence and associated factors of pulmonary hypertension in Kenyan children with adenoid or adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 2014;78(8):1381-6. [DOI:10.1016/j.ijporl.2014.06.002] [PMID]
16. Lima MS, Nader CMFF, Franco LP, Meira ZMA, Capanema FD, Guimarães RES, et al. Pulmonary hypertension evaluation by Doppler echocardiogram in children and adolescents with mouth breathing syndrome. Braz J Otorhinolaryngol 2017;83(3):292-8. [DOI:10.1016/j.bjorl.2016.03.020] [PMID] []
17. Orji FT, Ujunwa FA, Umedum NG, Ukaegbe O. The impact of adenotonsillectomy on pulmonary arterial pressure in West African children with adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 2017;92:151-5. [DOI:10.1016/j.ijporl.2016.11.023] [PMID]
18. Martha VF, da Silva Moreira J, Martha AS, Velho FJ, Eick RG, Goncalves SC. Reversal of pulmonary hypertension in children after adenoidectomy or adenotonsillectomy. Int J Pediatr Otorhinolaryngol 2013;77(2):237-40. [DOI:10.1016/j.ijporl.2012.11.006] [PMID]
19. Leiberman A, Stiller-Timor L, Tarasiuk A, Tal A. The effect of adenotonsillectomy on children suffering from obstructive sleep apnea syndrome (OSAS): the Negev perspective. Int J Pediatr Otorhinolaryngol 2006;70(10):1675-82. [DOI:10.1016/j.ijporl.2006.06.002] [PMID]
20. Eftekharian D, Beiranvand D, Rad D, Karimah D, Gachkar D. The effect of adenotonsillectomy on pulmonary artery pressure. Pajouhandeh J 2008;13(3):225-9. [URL]
21. Naiboglu B, Deveci S, Duman D, Kaya KS, Toros S, Kinis V, et al. Effect of upper airway obstruction on pulmonary arterial pressure in children. Int J Pediatr Otorhinolaryngol 2008;72(9):1425-9. [DOI:10.1016/j.ijporl.2008.06.005] [PMID]
22. Orji FT, Adiele DK, Umedum NG, Akpeh JO, Ofoegbu VC, Nwosu JN. The clinical and radiological predictors of pulmonary hypertension in children with adenotonsillar hypertrophy. Eur Arch Otorhinolaryngol 2017;274:1237-43. [DOI:10.1007/s00405-016-4207-y] [PMID]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
