Volume 35, Issue 4 (July 2024)                   Studies in Medical Sciences 2024, 35(4): 326-336 | Back to browse issues page


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Mojarrad A, Sadri Damirchi E, Sheykholeslami A, Rrezaeisharif A, Abbasi V. BRAIN STIMULATION AND COGNITIVE REHABILITATION: A DUAL APPROACH TO MANAGE AGGRESSION AND NOCTURNAL BEHAVIOR IN PATIENTS WITH MILD ALZHEIMER'S DISRASE. Studies in Medical Sciences 2024; 35 (4) :326-336
URL: http://umj.umsu.ac.ir/article-1-6080-en.html
Professor, Department of Counseling, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran (Corresponding Author) , e.sadri@uma.ac.ir
Abstract:   (198 Views)
Background & Aims: Alzheimer's disease is one of the most significant health issues of our time, affecting a large number of people. To mitigate its effects, various methods such as transcranial direct current stimulation (tDCS) and cognitive rehabilitation are employed. The aim of this study was to compare the effectiveness of tDCS and short-term cognitive rehabilitation protocols on aggressive symptoms and nocturnal behavior in patients with mild Alzheimer's disease.
Materials & Methods: This semi-experimental study included two experimental groups and one control group, using pre-test and post-test methods. The statistical population consisted of all elderly individuals over 65 years old with mild Alzheimer's who had consulted a neurologist in 2022. From this population, 60 individuals were selected through available sampling and then randomly assigned to either of the two experimental groups or the control group. The independent variables included direct current brain stimulation intervention (tDCS) for one experimental group, a short-term cognitive rehabilitation program for the second experimental group, and no intervention for the third group. Post-tests were conducted one week after the intervention on both experimental and control groups, followed by a follow-up after one month. A neuropsychological questionnaire (NPI) was used to collect data. Repeated measures analysis of variance was performed using SPSS-23 software, with a significance level set at
p < 0.05.

Results: The results indicated that both methods reduced aggressive symptoms in elderly individuals with mild Alzheimer's disease. However, neither method had a significant effect on reducing nocturnal behavior symptoms in these patients.
Conclusion: The findings suggest that both tDCS and short-term cognitive rehabilitation reduce aggressive symptoms in patients with mild Alzheimer's disease but do not significantly impact nocturnal behavior symptoms. Further studies are needed to confirm the role of these methods in addressing aggression and nocturnal behavior.
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Type of Study: Clinical trials | Subject: Neuroscience

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