Volume 34, Issue 4 (7-2023)
Studies in Medical Sciences 2023, 34(4): 191-195 |
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Shahhosseini E, Rahmani V. OVARIAN FIBROTHECOMA IN PREMENOPAUSAL WOMAN WITH RECENT AMENORRHEA: A CASE REPORT. Studies in Medical Sciences 2023; 34 (4) :191-195
URL: http://umj.umsu.ac.ir/article-1-5983-en.html
URL: http://umj.umsu.ac.ir/article-1-5983-en.html
Department of obstetrics and Gynecology, Faculty of medicine, Tabriz university of medical sciences, Tabriz, Iran (Corresponding Author) , Vahideh_rahmani@yahoo.com
Abstract: (1909 Views)
Background & Aims Fibroids are solid ovarian tumors, usually originating from connective tissue, that vary in size; from the small size of small nodules on the ovarian surface to large neoplasms weighing several kilograms.
Case presentation: a 43-year-old married woman, nulli gravida, without any past medical history,
who complained of Amenorrhea in six past recent months, was referred to our academic hospital in Tabriz, Iran. According to the size of the abdomen, it was not possible to determine the exact size of the uterus by pelvic examination. The laboratory test was normal, and CA-125 was 79.6. In CTS scan, mild pericardial effusion, massive pleural effusion in the right lung, and a solid cystic mass without a sharp limit with size of 114╳91╳91 mm above the uterus that probably was originated from left adnexa was reported. In the right adnexa, a mural nodule cystic lesian with size of 46╳43 mm with a huge amount of abdominal fluid was revealed. According to the patient's symptoms, resend abdominal distension, pain, and Amenorrhea, and medical imaging after counseling with the patient, she was referred to Hemato-oncologists, and nine sessions of chemotherapy was performed and again referred to CT scan. According to the observations of CT scan and clinical examination, the patient underwent laparotomy and bilateral salpingo-oophorectomy and myomectomy was performed.
The frozen section result was included fibro-thecoma, Adeno fibroma cyst, and uterine Leiomyoma, and so was benign.
Conclusion: In cases of accompanying ovarian mass with ascites and pleural effusion, and abnormal uterine bleeding pattern, it is very important to think about benign ovarian mass differential diagnosis such as Fibrothecoma with Meigs syndrome after removal of the ovarian neoplasm, and there is a prompt resolution of both abdominal and pleural fluid.
Case presentation: a 43-year-old married woman, nulli gravida, without any past medical history,
who complained of Amenorrhea in six past recent months, was referred to our academic hospital in Tabriz, Iran. According to the size of the abdomen, it was not possible to determine the exact size of the uterus by pelvic examination. The laboratory test was normal, and CA-125 was 79.6. In CTS scan, mild pericardial effusion, massive pleural effusion in the right lung, and a solid cystic mass without a sharp limit with size of 114╳91╳91 mm above the uterus that probably was originated from left adnexa was reported. In the right adnexa, a mural nodule cystic lesian with size of 46╳43 mm with a huge amount of abdominal fluid was revealed. According to the patient's symptoms, resend abdominal distension, pain, and Amenorrhea, and medical imaging after counseling with the patient, she was referred to Hemato-oncologists, and nine sessions of chemotherapy was performed and again referred to CT scan. According to the observations of CT scan and clinical examination, the patient underwent laparotomy and bilateral salpingo-oophorectomy and myomectomy was performed.
The frozen section result was included fibro-thecoma, Adeno fibroma cyst, and uterine Leiomyoma, and so was benign.
Conclusion: In cases of accompanying ovarian mass with ascites and pleural effusion, and abnormal uterine bleeding pattern, it is very important to think about benign ovarian mass differential diagnosis such as Fibrothecoma with Meigs syndrome after removal of the ovarian neoplasm, and there is a prompt resolution of both abdominal and pleural fluid.
Type of Study: case report |
Subject:
زنان و زایمان
References
1. David G Mutch, Krishnansu Tewari, Robert S Mannel, William T. Creasman. DiSaia and Creasman Clinical Gynecologic Oncology. 10th Ed. Elsevier Health Sciences; Philadelphia. 2022. https: //doi.org/10.1016/b978-0-323-77684-4.00004-0 [Google books]
2. Jonathan Berek, Neville F, Hacker, Berek and Hackers editors. Practical Gynecologic oncology. 7th ed. Philadelphia. 2020. [URL]
3. Obeidat RA, Aleshawi AJ, Obeidat HA, Al Bashir SM. A rare presentation of ovarian fibrothecoma in a middle age female: case report. Int J Womens Health 2019;11: 149-52.https: //doi.org/10.2147/ijwh.s191549 [DOI:10.2147/IJWH.S191549] [PMID] [PMCID]
4. Podfiguma-Stopa A, Czyzyk A, Katulski K, Moszynski R, Sajdak S, Genazzani AR, et al. Recurrent endometrial Hyperplasia as a presentation of estrogen-secreting thecoma case report and mini review of the literature. Gynecol Endocrinal 2016;32(3): 184-7. https: //doi.org/10.3109/09513590.2015.1113519 [DOI:10.3109/09513590.2015.1113519] [PMID]
5. Matalliotaki C, Matalliotakis M, Ieromonachou P, Goulielmos G, Zervou M, Laliotis A, et al. Co-existence of benign gynecological tumors with endometriosis in a group of 1,000 women. Oncol let 2018;15(2): 1529-32. https: //doi.org/10.3892/ol.2017.7449 [DOI:10.3892/ol.2017.7449] [PMID] [PMCID]
6. Krishnan D, Kumar K, Thomas A. Unilateral ovarian fibrothecoma with menorrhagia. J Pathol 2014;36(1): 55-8. [Google Scholar]
7. Shen Y, Liang Y, Cheng X, Lu W, Xie X, Wan X. Ovarian fibroma/fibrothecoma with elevated serum CA125 level. A cohort of 66 cases. Medicine 2018; 97(34): e11926. https: //doi.org/10.1097/md.0000000000011926 [DOI:10.1097/MD.0000000000011926] [PMID] [PMCID]
8. Parwate N, Patel S, Arora R, Gupta M. Ovarian fibroma: A clinico- pathological study of 23 cases with review of literature. J Obstet Gynecol India 2016;66(6): 460-5. https: //doi.org/10.1007/s13224-015-0717-6 [DOI:10.1007/s13224-015-0717-6] [PMID] [PMCID]
9. Salemis N, Panagiotopoulos N, Papamichaill V, Kiriakopoulos K, Niakas E. Bilateral ovarian fibrothecoma. An uncommon cause of a large pelvic mass. Int J Surg Case Rep 2011;2(3): 29-31. https: //doi.org/10.1016/j.ijscr.2010.07.005 [DOI:10.1016/j.ijscr.2010.07.005] [PMID] [PMCID]
10. Chen H, Liu Y, Li-Fei S, Jiang M, Yang ZF, Fang GP. Ovarian thecoma-fibroma groups: Clinical and sonographic features with pathological comparison J Ovarian Res 2016;9: 81. https: //doi.org/10.1186/s13048-016-0291-2 [DOI:10.1186/s13048-016-0291-2] [PMID] [PMCID]
11. Wu B, Peng J, Gu J, Cheng F, Mao J. MRI diagnosis of ovarian fibrothecomas: Tumour appearances and oestrogenic effect features. Br J Radiol 2014;87(1038): 20130634. https: //doi.org/10.1259/bjr.20130634 [DOI:10.1259/bjr.20130634] [PMID] [PMCID]
12. Sharma S, Bansal R, Upreti S, Khare A, Sharma S, Agarwal D. Ovarian fibrothecoma with extensive cystic degeneration: Two case reports. Indian J Clin Pract 2013;23(1): 840-1. [Google Scholar]
13. Chechia A, Attia L, Temime RB, Makhlouf T, Koubaa A. Incidence, clinical analysis, and management of ovarian fibromas and fibrothecomas. Am J Obstet Gynecol 2008;199(5): 473-4. https: //doi.org/10.1016/j.ajog.2008.03.053 [DOI:10.1016/j.ajog.2008.03.053] [PMID]
14. Vyas N, Manjeera L, Rai S. Delayed menopause at the age of 64 due to ovarian granulosa cell tumor. J Clin Diag Res;7(10): 2306 [] [PMCID]
15. Ayhan A, Siman MC, Velipasaoglu M, Sakinci M, Yuce K Prognostic factors in adult granulosa cell tumors of the ovary: A retrospective analysis of 80 cases J Gynecol Oncol 2009;20(3): 158-63. https: //doi.org/10.3802/jgo.2009.20.3.158 [DOI:10.3802/jgo.2009.20.3.158] [PMID] [PMCID]
16. Sheikh AA, Ganapathy H, Prijatham BO. Fibrothecoma a rare benign ovarian neoplasm. Sch J Med Case Rep 2017;5(1): 65-7.
17. Numanoglu C, Kuru O, Sakinci M, Akbayir O, Ulker V. Ovarian fibroma/fibrothecoma: Retrospective cohort study shows limited value risk of malignancy index score. Aust N Z J Obstet Gynaecol 2013;53(3): 287-92. https: //doi.org/10.1111/ajo.12090 [DOI:10.1111/ajo.12090] [PMID]
18. 18.Cho YJ, Lee HS, Kim JM, Joo KY, Kim ML. Clinical characteristics and surgical management options for ovarian fibroma/fibrothecoma: A study of 97 cases. Gynecol Obstet Invest 2013;76(3): 182-7. https: //doi.org/10.1159/000354555 [DOI:10.1159/000354555] [PMID]
19. Loue VS, Gbary E, Koui S, Akpa B, Kouassi A. Bilateral ovarian fibrothecoma associated with ascites, bilateral pleural effusion, and marked elevated serum CA-125. Case Rep Obst Gynecol 2013;2013: 189072. https: //doi.org/10.1155/2013/189072 [DOI:10.1155/2013/189072] [PMID] [PMCID]
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