Received: 13 January, 2009 Accepted: 4 Feb, 2009

  Abstract

  Background & Aims : Brucellosis is a widespread, economically devastating and highly infectious zoonosis. Mass immunization has become a favorite strategy to control of disease .in, this study, we tried to estimate marginal effectiveness of livestock immunization program in West-Azerbayjan province.

  Materials &Methods : Epidemiological data about of brucellosis was gathered through literature review, expert opinion, existing resources of data and synthesis by modeling of other data and transmission of disease pattern. In a state transition model different stages of disease and intervention in three scenario (cover of immunization with 50%, 80% and 0%)were simulated and estimate the economic benefit and cost –effectiveness through the control of brucellosis by mass vaccination of livestock.

  Results : In a scenario of cover with 50% reduction of brucellosis transmission between animals achieved to vaccination , estimated intervention costs were 102270000000R(Iranian Rials) & the overall disease cost reduction due intervention was 269124000000 R (Iranian Rials) and benefit-cost ratio is 322%. In a scenario of cover with 80%, estimated intervention costs were 163710000000R (Iranian Rials) & the overall disease cost reduction due intervention was 322125000000 R (Iranian Rials).

  Conclusion : Our study showed that effectiveness of immunization against brucellosis is quite significant. Calculation using basic estimates of cost of intervention program implies that this intervention is possibly very cost-effective and if with other interventions, such as control and limitation of livestock mobility, the eradication of disease is available aims.

  Keywords: Brucellosis, Immunization, Cost Effctiveness, Modelling, Livestock

  Address: Public Health Department, Health School, Nazlou Rade, Urmia, Iran, Tel: (+98441)2770047

  E-mail : rsljvd@yahoo.com

  Source : UMJ 2009: 20(1): 077 ISSN: 1027-3727