Background & Aims: Numerous studies showed that vitamin D has direct effect on the innate and acquired immune system. Serum levels of vitamin D play an important role in the incidence of infectious disease and also the outcome of its treatment.

Materials & Methods: In this observational and cross-sectional study, the serum levels of vitamin D, calcium, and, PTH in 44 patients with different forms of tuberculosis were compared with the control group.

Results: In this study serum level of vitamin D in patients (mean 15.07± 15.99) was significantly lower than the control group (mean: 16.88±9.88) (p = 0.05). Serum level of calcium in patients group (9.15±0.59) was significantly (P < 0.001) lower than the control group (9.53 ± 0.26). Serum level of PTH in patient group (33.08 ± 21.73) did not have significant difference with the control group (38.2 ± 19.1) (p = 0.178).

Conclusion: According to this study low serum level of vitamin D and calcium may be a risk factor for reactivation of TB in some patients.

SOURCE: URMIA MED J 2017: 27(11): 1002 ISSN: 1027-3727