Background & Aims: Hypercapnia cause to increase rate of emergence time from anesthesia and decrease spontaneous breathing onset time and extubation meaningfully. The aim of this study was evaluation of e ffects induced hypercapnia on emergence fro m anesthesia with propofol in elective surgery

 Materials & Methods : In a clinical trial studying that was perforemd in anesthesiology departemnt of Tabriz Univercity on patient that underwent elective surgery, we evaluated the effects of induced hypercapnia on emergence fro m anesthesia with propofol.

 Results : Accordinly, 38 patients in normocapnia group and 38 patients in hypercapnia group were evaluated. Average age of patients in normocapnia group was 33±11.27 and in hypercapnia group was 36.94±11.56 years (P=0.134). The Average time of eye opening in patients of normocapnia group was 11.92±1.97 and in hypercapnia group was 7.98±1.74 minutes (P<0.001). The average time of mouth opening in patients of normocapnia group was 12.78±1.90 and in hypercapnia group was 9.30±1.91 minutes (P<0.001). The Averag time of spontaneous breathing in patients of normocapnia group was 9.34±2.40 and in hypercapnia group was 4.53±1.44 minute (P<0.001). The average time of extubation in patients of normocapnia group was 10.76±2.28 and in hypercapnia group was 6.38±1.77 minutes (P<0.001).

 Conclusion : The Average time of eye and mouth opening, spontaneous starting breathing and extubation in patients of hypercapnia group was significantly lower than normocapnia group.

 SOURCE: URMIA MED J 2015: 26(1): 46 ISSN: 1027-3727