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URL: http://umj.umsu.ac.ir/article-1-1770-en.html
, Ali Nahali Moghaddam , Masomeh Hajishafiha , Mehrzad Sadaghiani , Fariba Nanbakhsh , Yaghob Deldar , Nahid Asadi , Nazila Kiarang , Vida Saidi
Received: 23 Apr , 2013
Accepted: 28 Jun , 2013
Background & Aims: Concentrations of certain substances in follicular fluid (FF) may
related to fertilization outcome. The study aim was to identify FF markers with
which to predict embryo implantation potential.
Materials & Methods: Concentrations of selected hormones, cytokines and growth factors in
FF samples obtained during assisted reproduction treatment, Intracytoplasmic
Sperm Injection (ICSI) method were related with treatment outcomes.
Results: Mean
concentrations of 17beta-estradiol (E2), prolactin (PRL) and insulin-like
growth factor (IGF)-I were significantly higher, in treatment attempts leading
to a clinical pregnancy as compared with those in which no pregnancy was
established. LH, growth hormone (GH), progesterone, and interleukin-1 (IL-1)
concentrations are similar in successful and unsuccessful attempts.
Conclusions: Fertilization
outcomes were related to FF levels of PRL, E2 and IGF-I. But LH, growth GH,
progesterone, and IL-1 are not markers of success.
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