Volume 19, Issue 1 (vol.19 , No.1 , spring 2008 2008)                   Studies in Medical Sciences 2008, 19(1): 86-89 | Back to browse issues page

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CAPTOPRIL-INDUCED ACUTE RENAL FAILURE IN BARTTER SYNDROME. Studies in Medical Sciences. 2008; 19 (1) :86-89
URL: http://umj.umsu.ac.ir/article-1-265-en.html
Abstract:   (17030 Views)

Bartter syndrome presenting in neonatal or early infancy is characterized by salt loosing tubulopathy, hypokalemia, and metabolic alkalosis. Failure to thrive is one of the most common findings in neonatal bartter syndrome. Angiotensin converting enzyme inhibitors are one of the therapeutic options for improving growth in these patients.

We describe a case of neonatal bartter syndrome with mild impairment of renal function for whom captopril started to promote better growth but she presented later with clinical and laboratory signs of exacerbation of renal impairment which were significantly resolved after discontinuing captopril.

In patients with Bartter syndrome and underlying renal dysfunction angiotensin converting enzyme inhibitors should be used with caution and low dose
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Type of Study: Research | Subject: آناتومی

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