Volume 25, Issue 2 (Monthly_April 2014)                   Studies in Medical Sciences 2014, 25(2): 97-104 | Back to browse issues page

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Gorashizadeh M A, Shaafee S, Herizchi Ghadim S, Pirzeh R, Safikhanlou S, Rikhtegar Ghiasi R et al . A STUDY OF SERTRALINE EFFICACY ON REDUCING DISABILITIES IN STROKE IN PATIENTS: A DOUBLE BLIND RANDOMIZED CLINICAL TRIAL. Studies in Medical Sciences 2014; 25 (2) :97-104
URL: http://umj.umsu.ac.ir/article-1-2156-en.html
Faculty of Medicine, Tabriz University of Medical Sciences, Razi Hospital, , Pirzehr@tbzmed.ac.ir
Abstract:   (16006 Views)


 Background & Aims: Stroke is a clinical syndrome characterized by focal neurologic deficits. It is classified as one of the most important causes of impairment. Stroke has a critically impairing effect on the life quality of patients. Considering the importance of the problem and its treatment, we aimed to study the effects of sertraline on reducing the disabilities in stroke.

 Materials & Methods: This double blind control trial study was conducted on 67 patients (completers: N=67, Mean age 65.27 ± 6.17) who were selected randomly and were assigned to receive 9 months of treatment with either sertraline or placebo.

 Results: The intervention group consisted of 40 patients from which three (7.5%) patients failed to be followed up because of the depression. The control group consisted of 40 patients and 11 (27.5%) were excluded during the study because of depression. There was a significant difference between the two groups regarding their sleep, social isolation, physical ability, emotional reaction and energy level, but the difference was not significant in pain scale.

 Conclusion : S ertraline could positively affect stroke patients in preventing several scales of quality of life, health profile and depression. 


  SOURCE: URMIA MED J 2014: 25(2): 104 ISSN: 1027-3727

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Type of Study: Research | Subject: آناتومی

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