Volume 22, Issue 2 (biomonthly 2011)                   Studies in Medical Sciences 2011, 22(2): 99-104 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Pourteymour Fard Tabrizi F, Alipoor B, Ostadrahimi A, MehrzadSadaghiani M. غلظت سرمی روی (Zn) و ارتباط آن با سطح انسولین سرم در زنان مبتلا به سندرم تخمدان پلی کیستیک. Studies in Medical Sciences 2011; 22 (2) :99-104
URL: http://umj.umsu.ac.ir/article-1-911-en.html
Tabriz University of Medical Sciences , balipoor@yahoo.com
Abstract:   (18209 Views)

Background & objective: Polycystic ovary syndrome is the most common endocrine disorder and main cause of infertility due to anovulation in reproductive aged women.With regard to the important role of insulin resistance and hyperinsulinemia in the pathophysiology of this syndrome and the role of zinc in structure and function of insulin hormone, as zinc dishomeostasis has adverse effect on the synthesis and secretion of insulin that lead to exacerbation of insulin resistance condition  therefore the aim of this study was to assess serum zinc and insulin concentrations in women with polycystic ovary syndrome.

Material & Methods: Sixty-five women with polycystic ovary syndrome who were referred to infertility and midwifery Clinic of Alzahra Women’s Hospital in Tabriz city, enrolled in this cross-sectional study. Serum zinc concentration was determined by flame atomic absorption spectrophotometry. Serum insulin level was measured with ELISA method and serum glucose level was measured by enzymatic glucose-oxidaze method. Statistical analyses were performed with descriptive-analytical methods. P-value < 0.05 was considered significant.

Results: In this study means of body mass index, waist circumference, fasting serum zinc, glucose, and insulin levels and mean intake of dietary zinc were: 29.39±1.65kg/m2, 97.24±6.42cm, 77.18±5.41µg/dl, 94.40±6.86 mg/dl, 18.33±8.24 µU/ml, 5.45±0.8 mg/day, respectively. There were significant negative relationships between serum zinc and serum insulin, insulin resistance index in women with polycystic ovary syndrome (r = -0.44, P= 0.001).

Conclusion: We recommend the nutritional-metabolic importance of zinc in polycystic ovary syndrome, and encourage the patients in consumption of zinc contents foods like marine meals and nuts.

Key Words: Polycystic ovary syndrome (PCOS), insulin resistance, serum zinc, insulin


Source: Urmia Med J 2011: 22(2): 163 ISSN: 1027-3727

Full-Text [PDF 233 kb]   (2277 Downloads)    
Type of Study: Research | Subject: آناتومی

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Studies in Medical Sciences

Designed & Developed by : Yektaweb