Volume 31, Issue 2 (May 2020)
Studies in Medical Sciences 2020, 31(2): 98-106 |
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vaghef L, soltani margani F, bafandeh gharamaleki H. EFFECTIVENESS OF TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) ON ATTENTION IN PEOPLE WITH DEPRESSION. Studies in Medical Sciences 2020; 31 (2) :98-106
URL: http://umj.umsu.ac.ir/article-1-4803-en.html
URL: http://umj.umsu.ac.ir/article-1-4803-en.html
Assistant Professor, Department of Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran (Corresponding Author) , L.vaghef@gmail.com
Abstract: (3881 Views)
Background & Aims: Impairment in executive functions such as attention is a common symptom of depression. The purpose of this investigation was to study the effect of transcranial direct current stimulation (tDCS) on attention in patients with depression.
Materials & Methods: Thirty subjects diagnosed with depressive disorder who were referred to the Counseling Center of Azerbaijan Shahid Madani University were selected using convenience sampling.
Then, the subjects were randomly divided into experimental and sham groups (n=15 per group). In order to investigate the effect of electrical stimulation on attention, the experimental group was exposed to anodal tDCS stimulation. The anode electrode was placed over the left DLPFC and the cathode electrode was placed over the right orbitofrontal cortex. The experimental group received tDCS stimulation with a current intensity of 2 mA, 20 min per session for 10 sessions. All subjects were evaluated before and after the tDCS intervention using classic stroop task. The obtained data were analyzed using multivariate analysis of covariance.
Results: The results showed that anodal tDCS stimulation resulted in a significant decrease in interference score in the experimental group.
Conclusion: According to the findings of the present research, application of anodal tDCS over the left DLPFC improves attention by reducing the interference effect in people with depression. Therefore, tDCS can be used as a safe and non-pharmacological intervention to improve attention in patients with depression.
Materials & Methods: Thirty subjects diagnosed with depressive disorder who were referred to the Counseling Center of Azerbaijan Shahid Madani University were selected using convenience sampling.
Then, the subjects were randomly divided into experimental and sham groups (n=15 per group). In order to investigate the effect of electrical stimulation on attention, the experimental group was exposed to anodal tDCS stimulation. The anode electrode was placed over the left DLPFC and the cathode electrode was placed over the right orbitofrontal cortex. The experimental group received tDCS stimulation with a current intensity of 2 mA, 20 min per session for 10 sessions. All subjects were evaluated before and after the tDCS intervention using classic stroop task. The obtained data were analyzed using multivariate analysis of covariance.
Results: The results showed that anodal tDCS stimulation resulted in a significant decrease in interference score in the experimental group.
Conclusion: According to the findings of the present research, application of anodal tDCS over the left DLPFC improves attention by reducing the interference effect in people with depression. Therefore, tDCS can be used as a safe and non-pharmacological intervention to improve attention in patients with depression.
Type of Study: Research |
Subject:
Neuroscience
References
1. Moayedoddin B, Rubovszky G, Mammana L, Jeannot E, Sartori M, Garin N, et al. Prevalence and clinical characteristics of the DSM IV major depression among general internal medicine patients. Eur. J. Intern. Med. 2013;24(8):763-6. [DOI:10.1016/j.ejim.2013.05.016] [PMID]
2. Martin LA, Neighbors HW, Griffith DM. The experience of symptoms of depression in men vs women: analysis of the National Comorbidity Survey Replication. JAMA psychiatry. 2013;70(10):1100-6. [DOI:10.1001/jamapsychiatry.2013.1985] [PMID]
3. Talebi M, Fathi-Ashtiani A. The effectiveness of transcranial Direct Current Stimulation of the brain (tDCS) on reducing depressive symptoms among people with Depressive Disorder. IJBS. 2015;9(1):95-101. [URL]
4. Mohamadi M, Mohaqeqi Kamal SH, Vameghi M, Rafiey H, Setareh Forouzan A, Sajjadi H. A meta-analysis of studies related prevalence of depression in Iran. JRH. 2017;7(1):581-93. [DOI:10.18869/acadpub.jrh.7.1.581]
5. Cooney G, Dwan K, Mead G. Exercise for depression. Jama. 2014;311(23):2432-3. [DOI:10.1001/jama.2014.4930] [PMID]
6. Majdi MR, Ghayour Mobarhan M, Salek M, Taghi M, Mokhber N. Prevalence of depression in an elderly population: A population-based study in Iran. Iran. J. Psychiatry Behav. Sci. 2011;5(1):17-21. [Google Scholar]
7. Association AAP. American Psychiatric Association DSM-5 Task Force. Diagnostic and Statistical Manual of Mental Disorders (DSM-5). [URL]
8. Siegle GJ, Thompson W, Carter CS, Steinhauer SR, Thase ME. Increased amygdala and decreased dorsolateral prefrontal BOLD responses in unipolar depression: related and independent features. Biol. Psychiatry. 2007;61(2):198-209. [DOI:10.1016/j.biopsych.2006.05.048] [PMID]
9. Smith R, Chen K, Baxter L, Fort C, Lane RD. Antidepressant effects of sertraline associated with volume increases in dorsolateral prefrontal cortex. J. Affective Disord. 2013;146(3):414-9. [DOI:10.1016/j.jad.2012.07.029] [PMID]
10. Aretouli E, Brandt J. Everyday functioning in mild cognitive impairment and its relationship with executive cognition. Int J Geriatr Psychiatry: A journal of the psychiatry of late life and allied sciences. 2010;25(3):224-33. [DOI:10.1002/gps.2325] [PMID] [PMCID]
11. Ebadi M, Hoseini F, Pahlevan F, Esmaeilzade Akhoundi M, Farhadi V, Asqari R. The effectiveness of Transcranial direct current stimulation (tDCS) on working memory in patients with major depression. Maj. Danishgah-i Ulum-i Pizishki-i Arak. 2017;20(5):38-47. [Google Scholar]
12. Derakhshi F, Reza M. Assessment of attention bias in the cognitive processing of neutral and emotional words Using semantic Strop test. Shenakht. 2014;1(1):23-30. [Google Scholar]
13. Palmwood EN, Krompinger JW, Simons RF. Electrophysiological indicators of inhibitory control deficits in depression. Biol. Psychol. 2017;130:1-10. [DOI:10.1016/j.biopsycho.2017.10.001] [PMID]
14. Kasschau M, Sherman K, Haider L, Frontario A, Shaw M, Datta A, et al. A protocol for the use of remotely-supervised transcranial direct current stimulation (tDCS) in multiple sclerosis (MS). JoVE. 2015; (106):e53542. [DOI:10.3791/53542] [PMID] [PMCID]
15. Flöel A. tDCS-enhanced motor and cognitive function in neurological diseases. Neuroimage. 2014;85:934-47. [DOI:10.1016/j.neuroimage.2013.05.098] [PMID]
16. Arastoo AA, Zahednejad S, Parsaei S, Alboghebish S, Ataei N, Ameriasl H. The effect of direct current stimulation in left dorsolateral prefrontal cortex on working memory in veterans and disabled athletes. Daneshvar. 2019;26(139):25-32. [Google Scholar]
17. Arkan A. Effect of transcranial direct current stimulation (tDCS) on working memory in healthy people. Brain Stimul. 2018;11(3):518-27. [DOI:10.1016/j.brs.2018.01.003] [PMID]
18. Plewnia C, Zwissler B, Längst I, Maurer B, Giel K, Krüger R. Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism. Cortex. 2013;49(7):1801-7. [DOI:10.1016/j.cortex.2012.11.002] [PMID]
19. Kuo M-F, Nitsche MA. Effects of transcranial electrical stimulation on cognition. Clin EEG Neurosci. 2012;43(3):192-9. [DOI:10.1177/1550059412444975] [PMID]
20. oraki m, shahmoradi s. The Effectiveness of Transcranial Direct Current Stimulation (TDCS) on the Working Memory and Severity of Depression Symptoms. Neuropsychology. 2019;4(15):75-88. [Google Scholar]
21. Fregni F, Boggio PS, Nitsche MA, Marcolin MA, Rigonatti SP, Pascual‐Leone A. Treatment of major depression with transcranial direct current stimulation. Bipolar Disord. 2006;8(2):203-4. [DOI:10.1111/j.1399-5618.2006.00291.x] [PMID]
22. Vaghef L, Bafandeh GHaramaleki H, Soltani Margani F. Effective of Transcranial Direct Current Stimulation (tDCS) on reaction time and risky Decision-Making in people with Depression. Neuropsychology. 2019;5(18):57-74. [Google Scholar]
23. Loo C, Alonzo A, Martin D, Mitchell P, Galvez V, Sachdev P. Transcranial direct current stimulation for depression: 3-week, randomised, sham-controlled trial. BJPsych. 2012; 200(1):52-9. [DOI:10.1192/bjp.bp.111.097634] [PMID]
24. Khani Pur P. The Effectiveness of Direct Brain Electrical Stimulation Therapy on Depression Symptoms and Attention of Depressed People in Ahvaz [Experimental]: Shahid Chamran University of Ahvaz; 2016. [URL]
25. Kasschau M, Sherman K, Haider L, Frontario A, Shaw M, Datta A, et al. A protocol for the use of remotely-supervised transcranial direct current stimulation (tDCS) in multiple sclerosis (MS). Journal of visualized experiments: JoVE. 2015; (106) [DOI:10.3791/53542] [PMID] [PMCID]
26. Fertonani A, Brambilla M, Cotelli M, Miniussi C. The timing of cognitive plasticity in physiological aging: a tDCS study of naming. Front Aging Neurosci. 2014;6:131. [DOI:10.3389/fnagi.2014.00131] [PMID] [PMCID]
27. MacLeod CM. Stroop effect. Encyclopedia of Color Science and Technology. 2016;1-6. [DOI:10.1007/978-3-642-27851-8_67-2]
28. Rajabi GR. Psychometric properties of Beck depression inventory short form items (BDI-13). J. Iran. Psychol. 2005;1(4):291-8. [Google Scholar]
29. Fregni F, Boggio PS, Nitsche MA, Rigonatti SP, Pascual‐Leone A. Cognitive effects of repeated sessions of transcranial direct current stimulation in patients with depression. Depress Anxiety. 2006;23(8):482-4. [DOI:10.1002/da.20201] [PMID]
30. Martin DM, Moffa A, Nikolin S, Bennabi D, Brunoni AR, Flannery W, et al. Cognitive effects of transcranial direct current stimulation treatment in patients with major depressive disorder: an individual patient data meta-analysis of randomised, sham-controlled trials. Neurosci Biobehav Rev. 2018;90:137-45. [DOI:10.1016/j.neubiorev.2018.04.008] [PMID]
31. Giordano J, Bikson M, Kappenman ES, Clark VP, Coslett HB, Hamblin MR, et al. Mechanisms and effects of transcranial direct current stimulation. Dose-Response. 2017;15(1):1559325816685467. [DOI:10.1177/1559325816685467] [PMID] [PMCID]
32. Bayat Mokhtari L, Agha Yousefi AR, Zare H, Nejati V. The Impact of Transcranial Direct Current Stimulation (TDCS) and Phonological Awareness Training on the Auditory Function of Working Memory in Children with Dyslexia. J. Except. Child. 2018;17(4):37-48. [URL]
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