Volume 32, Issue 2 (May 2021)                   Studies in Medical Sciences 2021, 32(2): 149-155 | Back to browse issues page

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Abbasi E, Ghazavi A, Nasimfar A, Mokhtari M. Evaluation of the Cerebrospinal Fluid Results Analysis and Culture in Infants under 18 Months with Simple Febrile Convulsion, Urmia Motahari Hospital, Iran, 2011 until 2016: A Retrospective Study. Studies in Medical Sciences 2021; 32 (2) :149-155
URL: http://umj.umsu.ac.ir/article-1-5424-en.html
Associate Professor of Pediatric Neurology,neurophysiology research center, Urmia University of Medical Sciences, Urmia, Iran (Correspondin Author) , Ghazavi.a@umsu.ac.ir
Abstract:   (3604 Views)
Background & Aims: This study aimed to evaluate the cerebrospinal fluid results analysis and culture in infants under 18 months with the diagnosis of simple febrile convulsion in Urmia Motahari hospital.
Materials & Methods: This retrospective descriptive study was conducted to evaluate the results of lumbar puncture in 223 infants under the age of 18 months with simple febrile seizures from 2011 to 2016. Patients’ information such as age and sex and the results of analysis and culture of cerebrospinal fluid culture were extracted from patients' records.
Results: Of 223 infants, 109 (48.8%) were male and 114 infants (51.2%) were female, with an average age of 9 months (age range between 5 to 15 months). Thirty-one of them (13.9%) had abnormal WBC (greater than 5/ mm3) and 192 (86.1%) had normal WBC (less than 5/ mm3). Twenty-four infants (10.8%) had an abnormal cerebrospinal fluid (protein more than 45 mg/dl) and 199 infants (89.2%) had normal cerebrospinal fluid (protein less than 45 mg/dl), 24 infants (10.8%) had abnormal CSF glucose level (less than 50 mg/dl) and 199 infants (89.2%) had normal CSF glucose level (more than 50 mg/dl). In 220 infants (99%), cerebrospinal fluid culture was negative and in 3 infants (1%), it was reported as unresponsive. Four out of 55 medical records (1.79%) were treated as bacterial meningitis and 5 (2.24%) of them were treated as aseptic meningitis.
Conclusion: Findings suggested that the patients under one year with febrile seizures should be carefully examined, regarding decision about conducting lumbar puncture (LP) for them.
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Type of Study: Research | Subject: کودکان (عمومی)

References
1. Sattar S, Saha S, Parveen F, Banu L, Momen A, Ahmed A, et al. Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam. Mymensingh medical journal: MMJ. 2014;23(4):676-85. [Google Scholar]
2. Pediatrics AAo. Neurodiagnostic evaluation of the child with a simple febrile seizure. Pediatrics. 2011;127(2):389. [DOI:10.1542/peds.2010-3318] [PMID]
3. Rosman NP. Evaluation of the child who convulses with fever. Pediatric Drugs. 2003;5(7):457-61. [DOI:10.2165/00128072-200305070-00003] [PMID]
4. Hoberman A, Wald ER. Urinary tract infections in young febrile children. The Pediatric infectious disease journal. 1997;16(1):11-7. [DOI:10.1097/00006454-199701000-00004] [PMID]
5. Kayastha N, Rai GK, Karki S. Use of Lumbar Puncture for First Episode of Febrile Seizure among Children 6 Months to 18 Months of Age: A Cross Sectional Study. Birat Journal of Health Sciences. 2018;3(2):399-402. [DOI:10.3126/bjhs.v3i2.20933]
6. Chung J, Ou X, Kulkarni RP, Yang C. Counting white blood cells from a blood smear using Fourier ptychographic microscopy. PloS one. 2015;10(7):e0133489. [DOI:10.1371/journal.pone.0133489] [PMID] [PMCID]
7. Son YY, Kim G-H, Byeon JH, Eun S-H, Eun B-L. Need for lumbar puncture in children younger than 12 months presenting with simple febrile seizure. Pediatric emergency care. 2018;34(3):212-5. [DOI:10.1097/PEC.0000000000000779] [PMID]
8. Kimia A, Ben-Joseph EP, Rudloe T, Capraro A, Sarco D, Hummel D, et al. Yield of lumbar puncture among children who present with their first complex febrile seizure. Pediatrics. 2010;126(1):62-9. [DOI:10.1542/peds.2009-2741] [PMID]
9. Ahmadzadeh J, Mansorian B, Attari MM-A, Mohebbi I, Naz-Avar R, Moghadam K, et al. The association between hematological parameters and metabolic syndrome in Iranian men: A single center large-scale study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2018;12(1):17-21. [DOI:10.1016/j.dsx.2017.07.044] [PMID]
10. Najaf-Zadeh A, Dubos F, Hue V, Pruvost I, Bennour A, Martinot A. Risk of bacterial meningitis in young children with a first seizure in the context of fever: a systematic review and meta-analysis. PLoS One. 2013;8(1):e55270. [DOI:10.1371/journal.pone.0055270] [PMID] [PMCID]
11. Galetto-Lacour A, Zamora SA, Andreola B, Bressan S, Lacroix L, Da Dalt L, et al. Validation of a laboratory risk index score for the identification of severe bacterial infection in children with fever without source. Archives of disease in childhood. 2010;95(12):968-73. [DOI:10.1136/adc.2009.176800] [PMID]
12. Rezaeian S, Ahmadzadeh J. Assessment of food habits and their association with cardiovascular risk factors in employees. International Journal of Collaborative Research on Internal Medicine and Public Health. 2012;4(4):339-43. [Google Scholar]
13. Ghotbi F, Shiva F. An assessment of the necessity of lumbar puncture in children with seizure and fever. Headache. 2009;2(1):0.006. [Google Scholar]
14. Davis J, Lehman E. Fever Characteristics and Risk of Serious Bacterial Infection in Febrile Infants. The Journal of emergency medicine. 2019;57(3):306-13. [DOI:10.1016/j.jemermed.2019.06.028] [PMID]
15. Bank AM, Bazil CW, editors. Emergency management of epilepsy and seizures. Seminars in neurology; 2019: Thieme Medical Publishers. [Google Scholar]
16. Osman NM, Gai JPG. Assessment of the necessity of routine lumber puncture among children with fever and convulsions. Sudan Journal of Medical Sciences. 2019;14(3):162-71. [DOI:10.18502/sjms.v14i3.5216]
17. Ameen DM, Hassan FA, Moosa AI. Is Lumbar Puncture Mandatory for First Simple Febrile Seizures Among Children 6 to 18 Months of Age. Kerbala Jorunal of Medicine. 2012;5(11):1262-7. [Google Scholar]
18. Ahmed M, Ejaz M, Jahangeer A, Khan S, Hashmi SSR, Jawaid T, et al. Frequency and Associated Factors of Parental Refusal to Perform Lumbar Puncture in Children with Suspected Central Nervous System Infection: A Cross-sectional Study. Cureus. 2019;11(9). [DOI:10.7759/cureus.5653]
19. Kimia AA, Capraro AJ, Hummel D, Johnston P, Harper MB. Utility of lumbar puncture for first simple febrile seizure among children 6 to 18 months of age. Pediatrics. 2009;123(1):6-12. [DOI:10.1542/peds.2007-3424] [PMID]
20. Sadek AA, Mohamad MA, Ali SH, Hassan IAA-A, Hussein MF. Diagnostic value of lumbar puncture among infants and children presenting with fever and convulsions. Electronic physician. 2016;8(4):2255. [DOI:10.19082/2255] [PMID] [PMCID]
21. Golestan M, Fallah R, Akhavan-Karbasi S. Evaluation of CSF in 100 children admitted with febrile seizures. SSU_Journals. 2009;16(5):3-7. [URL]
22. Ehsanipour F, Khodapanahandeh F, Aslani Z. The prevalence of meningitis in children with febrile seizure hospitalized at Hazrat Rasoul hospital (1997-2002). Razi Journal of Medical Sciences. 2005;11(44):907-11. [Google Scholar]
23. Siddiqui HB, Haider N, Khan Z. Frequency of acute bacterial meningitis in children with first episode of febrile seizures. JPMA The Journal of the Pakistan Medical Association. 2017;67(7):1054-8. [Google Scholar]
24. Guedj R, Chappuy H, Titomanlio L, Trieu TV, Biscardi S, Nissack‐Obiketeki G, et al. Risk of Bacterial Meningitis in Children 6 to 11 Months of Age With a First Simple Febrile Seizure: A Retrospective, Cross‐sectional, Observational Study. Academic Emergency Medicine. 2015;22(11):1290-7. [DOI:10.1111/acem.12798] [PMID]

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