Volume 32, Issue 7 (October 2021)
Studies in Medical Sciences 2021, 32(7): 548-557 |
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Hatamkhani S, Tajeri A, Shiva A, Valizadeh Hassanlouei M A, Sharifi H. DETERMINATION OF THE PREVALENCE AND CLINICAL OUTCOME OF STRESS-INDUCED HYPERGLYCEMIA IN ICU OF IMAM KHOMEINI HOSPITAL, URMIA. Studies in Medical Sciences 2021; 32 (7) :548-557
URL: http://umj.umsu.ac.ir/article-1-4810-en.html
URL: http://umj.umsu.ac.ir/article-1-4810-en.html
Shima Hatamkhani 
, Akbar Tajeri , Afshin Shiva * 
, Mohammad Amin Valizadeh Hassanlouei , Hamdollah Sharifi
, Akbar Tajeri , Afshin Shiva * , Mohammad Amin Valizadeh Hassanlouei , Hamdollah Sharifi
Patient Safety Research Center, Department of Clinical Pharmacy, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran (Corresponding Author) , shiva@umsu.ac.ir
Abstract: (2971 Views)
Background & Aims: Over the past decade, inpatient hyperglycemia has become a major focus, due to its association with increased mortality, hospitalization complications, and its negative economic impact. Patients with hyperglycemia have greater mortality, postoperative stroke, and longer length of stay. Therefore, the aim of this study was to determine the prevalence of hyperglycemia and its therapeutic approach in the Intensive Care Unit (ICU).
Materials & Methods: This descriptive study was perfumed in the ICU of Imam Khomeini Educational Hospital in Urmia in 2016-2017. According to sample size determination, about 120 patients who were admitted to ICU for more than 24 hours were enrolled. The AACE / ADA 2009 guideline was used as a standard for hyperglycemic stress control.
Results: The records of 120 non-diabetic patients were studied for stress-induced hyperglycemia. The rate of stress-induced hyperglycemia was 19.2%. The mean age of the patients was 39 ± 24 years. The most common cause of hospitalization in ICU was traumatic problems (37.5%). About 57% of patients with hyperglycemia received intravenous feeding, 60.9% received corticosteroids, and 39.1% received vasopressor. Twenty-one (86.9%) patients used the SSI method and 3 (13.1%) used the infusion technique. The mortality rate was 35% for the patients admitted and 60.9% for patients with hyperglycemia.
Conclusion: In this study, the prevalence of hyperglycemia in the ICU was similar and relatively high in almost the same studies. Therefore, it seems that 6-hour blood glucose control has a better effect than once a day. In this study, most patients received SSI insulin for controlling hyperglycemia, while according to AACE / ADA 2009 guideline, the insulin infusion method is more appropriate. Therefore, in order to reduce hypoglycemia and mortality, it is recommended to use the insulin infusion technique to control hyperglycemia.
Materials & Methods: This descriptive study was perfumed in the ICU of Imam Khomeini Educational Hospital in Urmia in 2016-2017. According to sample size determination, about 120 patients who were admitted to ICU for more than 24 hours were enrolled. The AACE / ADA 2009 guideline was used as a standard for hyperglycemic stress control.
Results: The records of 120 non-diabetic patients were studied for stress-induced hyperglycemia. The rate of stress-induced hyperglycemia was 19.2%. The mean age of the patients was 39 ± 24 years. The most common cause of hospitalization in ICU was traumatic problems (37.5%). About 57% of patients with hyperglycemia received intravenous feeding, 60.9% received corticosteroids, and 39.1% received vasopressor. Twenty-one (86.9%) patients used the SSI method and 3 (13.1%) used the infusion technique. The mortality rate was 35% for the patients admitted and 60.9% for patients with hyperglycemia.
Conclusion: In this study, the prevalence of hyperglycemia in the ICU was similar and relatively high in almost the same studies. Therefore, it seems that 6-hour blood glucose control has a better effect than once a day. In this study, most patients received SSI insulin for controlling hyperglycemia, while according to AACE / ADA 2009 guideline, the insulin infusion method is more appropriate. Therefore, in order to reduce hypoglycemia and mortality, it is recommended to use the insulin infusion technique to control hyperglycemia.
Keywords: Stress-induced Hyperglycemia, ICU, Mortality, Sliding Scale Insulin, Insulin Infusion, AACE / ADA 2009 guidelines
Type of Study: Research |
Subject:
فارماکولوژی
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