Background & Aims : Man in all historical periods had to use domestic and medicine herbal plants. Over the last half century, the use of synthetic and chemical drugs is highly prevalent. The harmful effect of chemical drugs on human life has increased the tendency to use medicinal plants once more. The aim of this study was to investigate the effect of Avena sativa active ingredients on the wound healing and skin inflammation on the rat model.

  Materials & Methods : Extract of water, methanol and ethanol Avena sativa seeds were prepared by water distillation and Soxhlet systems. The components of all samples were determinate using TLC experiment. Thirty male Wistar rats in five groups were used in this experimental study and the rats were anesthetized with Ketamin (1 mg/kg), and standard ulcer (2 cm) was induced on the shaved dorsal by scatter.

  Result : The results of this experiment showed that all extracts decreased the time of wound healing significantly in comparison with the controls groups. There was no symptom of colloid even scar

  Conclusion : These extracts seem to accelerate the formation of the epidermis and causes wound healing. Total extract of Avena sativa has an important role in wound healing.

    Source: Urmia Med J 2011: 22(5): 484 ISSN: 1027-3727