Volume 33, Issue 6 (September 2022)
Studies in Medical Sciences 2022, 33(6): 466-477 |
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Research code: A-10-4737-1
Ethics code: IR.IAU.SEMNAN.REC.1398.002
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Zarezadeh T, Nemati N, ramezanzade H, Bagherpoor T. THE EFFECT OF PRENATAL EXERCISES ON PRETERM CHILDBIRTH AND NEONATAL CONSEQUENCES AND OUTCOMES IN PRIMIPAROUS PREGNANT WOMEN: A RANDOMIZED CONTROLLED CLINICAL TRIAL STUDY. Studies in Medical Sciences 2022; 33 (6) :466-477
URL: http://umj.umsu.ac.ir/article-1-5384-en.html
URL: http://umj.umsu.ac.ir/article-1-5384-en.html
PhD in Sports Management, Associate Professor, Department of Sports Sciences, Damghan Branch, Islamic Azad University, Damghan, Iran (Corresponding Author) , Nnemati258@gmail.com
Abstract: (1902 Views)
Background & Aims: Preterm childbirth refers to the birth of a live child before gestational age of 37 weeks, and is one of the most important determinants of neonatal morbidity and mortality throughout the world. The present study aims to determine the effect of prenatal exercise on preterm childbirth and neonatal consequences and outcomes in primiparous pregnant women.
Materials & Methods: The present study was enrolled on 80 healthy primiparous pregnant women of Damghan city who met the conditions to enter the study in 2020 and randomization was carried out online.
The supervised sports included: individual walking two days a week with self- chosen intensity based on the principle of load increase as well as sitting palates along with stand pregnancy aerobics with moderate intensity three times a week and each time was 45 minutes, which started from 18 to 20 weeks and continued until 37 to 39 weeks of pregnancy. The comparison group had usual care during pregnancy. Multivariate analysis of variance and independent t test were used to compare two groups.
Results: There was no significant difference in the rate of preterm birth in the two groups. The results of independent t-tests showed that there is a significant difference in the Apgar variables of the first minute (p=0.017) and oxygen saturation (p=0.001) between the two intervention and comparison groups. Also, the results of this research showed that there was a relationship between the group (intervention or comparison) and neonatal outcome (positive or negative) and being in the intervention group is a predictor of positive neonatal outcome.
Conclusion: Besides having a positive effect on neonatal outcomes (Apgar score and oxygen saturation), regular and managed exercise leads to positive outcomes in neonatal outcomes, especially reducing hospitalizations.
Materials & Methods: The present study was enrolled on 80 healthy primiparous pregnant women of Damghan city who met the conditions to enter the study in 2020 and randomization was carried out online.
The supervised sports included: individual walking two days a week with self- chosen intensity based on the principle of load increase as well as sitting palates along with stand pregnancy aerobics with moderate intensity three times a week and each time was 45 minutes, which started from 18 to 20 weeks and continued until 37 to 39 weeks of pregnancy. The comparison group had usual care during pregnancy. Multivariate analysis of variance and independent t test were used to compare two groups.
Results: There was no significant difference in the rate of preterm birth in the two groups. The results of independent t-tests showed that there is a significant difference in the Apgar variables of the first minute (p=0.017) and oxygen saturation (p=0.001) between the two intervention and comparison groups. Also, the results of this research showed that there was a relationship between the group (intervention or comparison) and neonatal outcome (positive or negative) and being in the intervention group is a predictor of positive neonatal outcome.
Conclusion: Besides having a positive effect on neonatal outcomes (Apgar score and oxygen saturation), regular and managed exercise leads to positive outcomes in neonatal outcomes, especially reducing hospitalizations.
Type of Study: Clinical trials |
Subject:
زنان و زایمان
References
1. Cunningham F, Leveno K, Bloom S, Spong CY, Dashe J. Williams Cunningham obstetrics. 25ed. Volum 1, Mcgraw-hill. 2018. P. [URL]
2. Steer P. The epidemiology of preterm labour. Int J Obstetr Gynaecol 2005;112(1):1-3
https://doi.org/10.1111/j.1471-0528.2005.00575.x [DOI:10.1111/j.1471-0528.2005.00837.x] [PMID]
3. Yousefi Z, KhaieKaramoddin M, Vahedian M, Ahmadian H, Prevalence of vaginal infections during pregnancy and its association with preterm birth. Journal of Medical Sciences and Health Services. J Shahid Sadoughi Univ Med Sci 2001;10:65. (Persian) [URL]
4. Vakilian K, Ranjbaran M, Khorsandi M, Sharafkhani N, Khodadost M. Prevalence of preterm labor in Iran: A systematic review and meta-analysis. Int J Reprod BioMed 2015;13(12):743-8 [DOI:10.29252/ijrm.13.12.743] [PMID] [PMCID]
5. Davenport MH, Meah VL, Ruchat SM, Davies GA, Skow RJ, Barrowman N, Adamo KB, et al. Impact of prenatal exercise on neonatal and childhood outcomes: a systematic review and meta-analysis. Br J Sport Med 2018; 52(21):1386-96.
https://doi.org/10.1136/bjsports-2018-099836 [DOI:10.1136/bjsports-2018-099697] [PMID]
6. Krassovskaia PM, Chaves AB, Houmard JA, Broskey NT. Exercise during Pregnancy: Developmental Programming Effects and Future Directions in Humans. Int J Sports Med 2022;43(02):107-18. doi: 10.1055/a-1524-2278. Epub 2021 Aug 3 PMID: 34344043 DOI: 10.1055/a-1524-2278. [DOI:10.1055/a-1524-2278] [PMID]
7. Kelly RE, Barakat R, Brown WJ, Dargent-Molina P, Haruna M, Mikkelsen EM, Mottola MF, et al. Guidelines for Physical Activity during Pregnancy: Comparisons From Around the World. Am J Lifestyle Med 2015;8(2):102-21. [DOI:10.1177/1559827613498204] [PMID] [PMCID]
8. Çırak Y, Yılmaz GD, Parlak Demir Y, Dalkılınç M, Yaman S. Pregnancy physical activity questionnaire (PPAQ): reliability and validity of Turkish version. J Physical Therap Sci 2015;27(12):3703-9. [DOI:10.1589/jpts.27.3703] [PMID] [PMCID]
9. Robin E. exercise during pregnancy among us women, from the Carolina Population Center and Department of Epidemiology, University of North Carolina Chapel Hill, NS, USA, 2013.
10. Shana G S, Luiza IR, Kelly RE, Pedro C. Leisure-Time physical Activity in Pregnancy and Maternal-Child Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Cohort Studies. Sports Med 2016;47(2):295-317. [DOI:10.1007/s40279-016-0565-2] [PMID]
11. Biase ND, Balducci S, Lencioni C, Bertolotto A, Tumminia A, Dodesini AR, et al. Review of general suggestions on physical activity to prevent and treat gestational and pre-existing diabetes during pregnancy and in postpartum. Nutr Met Cardiovasc Dis 2019;29(2):115-26. [DOI:10.1016/j.numecd.2018.10.013] [PMID]
12. Hardani A K, Nili F, Shariat M, Nayeri F, Dalili H. Conventional versus combined apgar scores in neonatal asphyxia: a prospective study. Tehran Univ Med J 2015;72(10):717-22. [Google Scholar]
13. Gafari H, Hidarzadeh M, Habibollahi, A. Healthy Neonatal Service Package, Neonatal Health Administration, Population Health Office, Family and Schools Ministry of Health. Ideparazan Fan va Honar. Tehran, Iran, 2012. (Persian)
14. Miller S, Whalen K. Adrenal Hormones. In: Whalen K, Field C, Radhakrishnan Lippincott® Illustrated Reviews: R (eds): Pharmacology. 7th edtion. Wolters Kluwer: Philadelphia. 2019; 965-984.
15. Apgar VA. Proposal for a new method of evaluation of the newborn infant. Current Researches in Anesthesia and Analgesia. 1953; 32(4): 260-267. [DOI:10.1213/00000539-195301000-00041] [PMID]
16. Martin RMD, Deakins KM. Respiratory support, oxygen delivery, and oxygen monitoring in the newborn. Literature Review Current. 2019; 1-10. [Google Scholar]
17. Zarezadeh T, Nemati N. Effects of 8 week regular walking on the neonate in nulliparous women. Koomesh. 2016; 17(2), 403-10 (Persian). [Google Scholar]
18. Mokaberian M, Farokhi A, Tahmasebi Sh. The effect of exercise during pregnancy on health indexes of infants. Motor Behav 2015;18:71-84. [Google Scholar]
19. Zarezadeh T, Nemati N. Effect of regular walking with self-selected intensity on neonatal Apgar score and Spo2 in nulliparous women:a clinical trial. Fifth Congress of Self-care Tehran University of Medical Sciences. IRAN. 2018 (Persian). [Google Scholar]
20. Bakhshande M, Poraram H, Torkestani F, Torabi P, Abedini M. Feeding of pregnant and lactating mothers, Office of Community Nutrition, Iran, Department of Health, Ministry of Health and Medical Education, Second Edition, 2014; p.14. )Persian(
21. Sultan S, Alzahrani N, Al-Sakkaf K.The postpartum effect of maternal diabetes on the circulating levels of sirtuins and superoxide dismutase. FEBS Open Bio 2018;8(2):256-63. doi: 10.1002/2211-5463.12370. eCollection 2018 Feb [DOI:10.1002/2211-5463.12370] [PMID] [PMCID]
22. Piravej K, Saksirnukili R. survey of patterns attitude, and the general effects of exercise during pregnancy in 203 Thai pregnancy women at king chulalongkorn Memorial hospital. J Med Assoc Thai 2001; (1):274-82. [Google Scholar]
23. Abbaszadeh F, Baghery A, Mehran N. Quality of Life among Pregnant Women. J Hayat 2009;15(1):41-8 (Persian). [Google Scholar]
24. Mohammadi M, Janani L. Randomization in randomized clinical trials: From theory to practice]. Hayat, Journal of School of Nursing and Midwifery, Tehran Univ Med Sci 2016;22(2):102-14. (Persian). [Google Scholar]
25. Riemann MK, Kanstrup Hansen IL. Effects on the foetus of exercise in pregnancy. Scandinavian J Med Sci Sports Med 2000;10(1):9-12. [DOI:10.1034/j.1600-0838.2000.010001012.x] [PMID]
26. VanRaaij JM, schonk CM, vermaat SH, Hautrast JG. Energy cost of walking at a fixed race and self-paced before, during, and after pregnancy. Am J Clin Nutr 1990;51(2):158-61. [DOI:10.1093/ajcn/51.2.158] [PMID]
27. Aghaalinejd A, Rahimi H, Siahkohial M. Applied physiology. First edition, Sport Medicine press institute of physical education, Tehran. 2012;1134-5. [URL]
28. Gafari pardasti. Healthy new borncare service package. Idea Pardazan Fan va Honar, Tehran, 1390. (Persian).
29. Habibollahi A. Acute care of at-risk newborn. Idea Pardazan Fan va Honar, Tehran, 1390. (Persian). [URL]
30. Danielle B. Cooper 1, Lily Yang. Pregnancy And Exercise In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [URL]
31. Daniele D, Mascio DD, Magro-Malosso ER, Saccone G, Marhefka GD, Berghella V. Exercise during pregnancy in normal-weight women and risk of preterm birth: a systematic review and meta-analysis of randomized controlled trials. American J Obstetr Gynecol 2016; (215(5):561-71 [DOI:10.1016/j.ajog.2016.06.014] [PMID]
32. Takami M, Tsuchida A, Takamori A, Aoki S, Ito M, Kigawa M, et al. Effects of physical activity during pregnancy on preterm delivery and mode of delivery: The Japan Environment and Children's Study, birth cohort study. PLoS One 2018;13(10):e0206160. [DOI:10.1371/journal.pone.0206160] [PMID] [PMCID]
33. Mehran N, Abaszadeh F, Bagheri A. Study of Relation between Physical Activity and Preterm Birth. Qom Univ Med Sci J 2012;6(1):17-22. [URL]
34. Duncombe D, Skouteris H, Wertheim EH, Kelly L, Fraser V, Paxton SJ. Vigorous exercise and birth outcomes in a sample of recreational exercisers: a prospective study across pregnancy. Aus New Zealand J Obstetr Gynaecol 2006;46(4):288-92. [DOI:10.1111/j.1479-828X.2006.00594.x] [PMID]
35. Clapp JF, Capeless EL. Neonatal morphometrics after endurance exercise during pregnancy. Am J Obstetr Gynecol 1990;163(6 pt 1):1805-11. [DOI:10.1016/0002-9378(90)90754-U] [PMID]
36. Alizadeh R, Sehati Shafaei F, Gojazadeh M, Kamali Fard M. The Effect of Lifestyle on the Rate of Preterm Birth. J Ardabil Univ Med Sci 2010;10(1): 55-6. (Persian) [Google Scholar]
37. Thangaratinam S, Rogozinska E, Jolly K, Glinlowski S, Rosenboom T, Tomlinson JW, Kunz R, Mol BW, et al. Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomized evidence. BMJ Lead General Med J 2012;16:344.
https://doi.org/10.1136/bmj.e2088 [DOI:10.1097/OGX.0b013e31826f78d9] [PMID] [PMCID]
38. Muktabhant TA, Lawrie P, Lumbiganon M, Laopaiboon. Diet or exercise, or both, for preventing excessive weight gain in pregnancy. Cochrane Database Sys Rev 2015;15(6):CD000180. [DOI:10.1002/14651858.CD007145.pub3] [PMID] [PMCID]
39. Memari A, Ramim T, Amini M, Agorlo A, Mehran A. Effects of aerobic exercise on pregnancy outcomes. J Nurs Midwifery 2006;12(3):35-40. (Persian) [URL]
40. Sedaghati P, Arjmand A, Sedaghati N. Do regular exercise and a bicycle ergometer impact on pregnancy outcomes? J Pediatr 2006;16(3):331-5. (Persian). [URL]
41. Zhu Z, Xie H, Liu S, Yang R, Yu J, Yan Y, et al. Effects of physical exercise on blood pressure during pregnancy. BMC Public Health 2022;22(1):1733. [DOI:10.1186/s12889-022-14074-z] [PMID] [PMCID]
42. Kardel KR, Kase T. Training in pregnant women: effects on fetal development and birth. Am J Obstetr Gynecol 1998;178(2):280-6. [DOI:10.1016/S0002-9378(98)80013-6] [PMID]
43. Chen Y, Ma G, Hu Y, Yang Q, Deavila JM, Zhu MJ, et al. Effects of maternal exercise during pregnancy on perinatal growth and childhood obesity outcomes: A meta-analysis and meta-regression. Sports Med 2021;51(11):2329-47.
https://doi.org/10.1007/s40279-021-01512-y [DOI:10.1007/s40279-021-01499-6]
44. Hall DC, Kaufmann DA. Effect of aerobic and strength conditioning on pregnancy outcome. Am J Obstetr Gynecol 1978;157(5):1199-1203. [DOI:10.1016/S0002-9378(87)80294-6] [PMID]
45. Du MC, Ouyang YQ, Nie XF, Huang Y, Redding SR. Effects of physical exercise during pregnancy on maternal and infant outcomes in overweight and obese pregnant women: A meta-analysis. Birth 2019;46(2):211-221. doi: 10.1111/birt.12396. Epub 2018 Sep 21. PMID: 30240042. [DOI:10.1111/birt.12396] [PMID]
46. Haj Kazemi E, Heidari M, Faizi Z, Haqqani H. The effect of exercise during pregnancy on pregnancy outcome. Iran J Nurs Midwifery Res 2000;13(25):1-9. (Persian) [URL]
47. Sternfeld B. Physical activity and pregnancy outcome. Review and recommendations. Sports Med 1997;23:33-47. [DOI:10.2165/00007256-199723010-00004] [PMID]
48. Ribeiro MM, Andrade A, Nunes I. Physical exercise in pregnancy: Benefits, risks and prescription. J Perinatal Med 2022;50(1):4-17. [DOI:10.1515/jpm-2021-0315] [PMID]
49. Wolfe LA, Lowe-Wyldem SJ, Tranmer JE, McGrath MJ.Fetal heart rate during maternal static exercise. Canadian J Sport Sci 1988;13:95.
50. Mohagheghy P. Neonatal equipment provision and maintenance, Idea Pardazan Fan va Honar, Tehran, 2011 (Persian) [URL]
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