TY - JOUR JF - URMIAMJ JO - Studies in Medical Sciences VL - 25 IS - 5 PY - 2014 Y1 - 2014/7/01 TI - SERUM LEVELS OF FETUIN-A AND ITS RELATIONSHIP WITH INTACT PARATHYROID HORMONE AND 25OH VITAMIN D IN HEMODIALYSIS PATIENTS TT - مطالعه سطح سرمی فتوئین آ و ارتباط آن با سطوح ویتامین D و iPTH بیماران تحت همودیالیز N2 -    Background & Aims: Fetuin-A is a circulating protein and a powerful circulating inhibitor of vascular calcification. It has been shown that Fetuin–A interactions with vascular vitamin D receptors may be an important key in preventing renal calcification. The aim of the present study was evaluating the levels of vitamin D (Vit D), intact Parathormone hormone(iPTH) and their relationship with that of Fetuin-A as the main factor involved in vascular calcification in patients suffering from heart diseases (HD).  Materials & Methods: The serum levels of iPTH, Fetuin-A, 25OH vitamin D, calcium, and phosphorus were determined in forty six hemodialysis (28 men and 18 women) and fort three age and sex matched control subjects (20 men and 23 women) by enzyme-linked immunosorbent assay and spectrophotometric methods. Results: In HD patients Fetuin-A and Vit D levels were significantly lower than the healthy controls (p = 0.004 and p=0.002 respectively). Serum iPTH and phosphorus concentrations were higher in HD patients compared to the healthy control group (p SP - 397 EP - 404 AU - Valizadeh Shahbazlou, Shahnam AU - Ghorbanihaghjo, Amir AU - Samadi, Naser AU - Rashtchizadeh, Nadere AU - Arghani, Hasan AU - Hallajzadeh, Jamal AU - Ablhasani, Sakhavat AD - Clinical Biochemistry Department, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran KW - Fetuin A KW - Vitamin D and Intact Parathyroid Hormone KW - Hemodialysis Patients UR - http://umj.umsu.ac.ir/article-1-2322-en.html ER -