TY - JOUR T1 - THE EFFECT OF EXERCISE TYPE ON THE EXPRESSION OF PGC-1A AND HEART TISSUE TRIGLYCERIDE CONTENT IN RATS WITH FATTY LIVER (NAFLD) TT - اثر نوع تمرین ورزشی بر بیان ژن PGC-1a و محتوای TG قلبی در رت‌های مبتلا به بیماری کبد چرب غیرالکلی (NAFLD) JF - URMIAMJ JO - URMIAMJ VL - 31 IS - 4 UR - http://umj.umsu.ac.ir/article-1-5114-en.html Y1 - 2020 SP - 282 EP - 294 KW - Low-Intensity Endurance Training KW - High-Intensity Interval Training KW - PGC-1a KW - Heart Tissue KW - Triglyceride N2 - Background & Aims: PGC-1a is one of the most important regulators of cardiac mitochondrial biogenesis which plays a key role in lipid oxidation processes. The aim of this study was to investigate the effect of low-intensity endurance training and high-intensity interval training on the expression of PGC-1a and heart tissue triglyceride content in rats with fatty liver (NAFLD). Materials & Methods: This experimental study was performed on 40 male Wistar rats. Rats were randomly divided into 4 groups. The control group received low-intensity endurance training and intense interval training that consumed high fat diet for 16 weeks and then the two training groups participated in the exercise program for 8 weeks. Also, the sham group used standard food during this time. Finally, expression levels of PGC-1a and intracellular adipose tissue of the four groups were measured. Results: The results showed that expression of PGC-1a increased after endurance training and intense interval training in cardiac tissue of obese male rats. Also, both types of intense intermittent exercise and low-intensity endurance training significantly decreased the fat content of cardiac tissue (p<0/05). Conclusion: The results showed that exercise training can increase the expression of PGC-1a and decrease the triglyceride content of the heart tissue in people with non-alcoholic fatty liver disease, indicating that exercise training can be a non-medicinal treatment for these people to use. M3 ER -