2024-03-29T13:26:06+03:30
http://umj.umsu.ac.ir/browse.php?mag_id=32&slc_lang=fa&sid=1
32-783
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
ANTIOXIDATIVE EFFECT OF HYPOTAURIN ON SUPPRESSION OF OXIDATIVE TENSION-INDUCED DAMAGE ON THE DEVELOPMENT OF MOUSE EMBRYO FERTILIZED IN VITRO
Abbas
Ahmadi
abbasahmadi60@yahoo.com
Rajabali
Sadrkhanloo
Received: 16 Sep, 2010 Accepted: 18 Oct, 2010
Abstract
Background &Aims : There are multiple mechanisms of embryo protection against ROS. However, in the in vitro condition these reagents are absent and the level of ROS is higher. This study was aimed to survey the morphological damage induced by oxidative stress and also to study the effect of Hypotaurin as an antioxidant on mouse preimplantation embryo development in two different conditions of normal and oxidative tension In vitro .
Material & Methods : Following in vitro fertilization, the zygotes were cultured in different groups in HTF medium containing 4 mg/ml BSA. To survey the effect of oxidative stress on embryo development, zygotes were cultured for one hour in a medium containing different concentrations of H2O2 and were transferred to the culture after washing. In order to study the effect of Hypotaurin on embryo development in oxidative tension system, the zygotes were placed in a medium containing different concentrations of Hypotaurin after culturing the zygotes in 10 µM H2O2 for 1 hour. Along with the effect of Hypotaurin on embryo development was surveyed by adding different concentrations of Hypotaurin to the culture without oxidative tension.
Results: After short time exposure to H2O2, the preimplantation embryo development decreased significantly and this was more obvious in higher concentrations. Hypotaurin reduced the impairment resulting from oxidative tension slightly and improved the embryo development, quality, and the cleavage rate and decreased embryo arrest. It also improved the cultured embryos morphologically (p<0.05).
Conclusion : To suppress the deleterious effects of ROS in embryo culture system various antioxidants can be employed. The present study showed that oxidative stress induced embryo arrest and dismorphogenesis and reduced the embryo development. However, supplementation of the embryo culture with Hypotaurin improved the embryo. Therefore,�adding antioxidants such as Hypotaurin to embryo culture system restores the embryo growth from damages.
Source: Urmia Med J 2010: 21(4): 381 ISSN: 1027-3727
ROS
Zygote
Embryo arrest
Hypotaurin
Mouse
2010
12
01
306
317
http://umj.umsu.ac.ir/article-1-783-en.pdf
32-784
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
COMPARISON SERUM LEVELS OF IRON, ZINC, COPPER, MAGNESIUM AND HAEMATOLOGICAL INDEXES IN BLASTOCYSTIS INFECTED PATIENTS AND HEALTHY CONTROLS
Ali
Moosavi
Ahmad Reza
Meamar
meamar@iums.ac.ir
Lame
Akhlaghi
Rahele
Rafiei Sefiddashti
Hormozd
Oormazdi
Elham
Razmjou
Mohsen
Firoozrai
Hassan
Shojaee
Blastocystis
Iron
Zinc
Copper
Magnesium
Hematological indexes
2010
12
01
318
323
http://umj.umsu.ac.ir/article-1-784-en.pdf
32-785
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
EVALUATION OF CHEMICAL COMPOSITION AND ANTIBACTERIAL EFFICACY OF CUMINUM CYMINUM L. AND MENTHA LONGIFOLIA L. ALONE AND COMBINED WITH NISIN
Mohammad Reza
Pajohi
Hossein
Tajik
h.tajik@urmia.ac.ir
Afshin
Akhondzade
Hassan
Gandomi
Ali
Ehsani
Farnood
Shokohi Sabet Jalali
Received: 25 Aug, 2010 Accepted: 16 Oct, 2010 Abstract Background & A ims : Mentha longifolia and cumin seed were used for long time as spices and in conventional medicine . T his study was undertaken in order to evaluate the chemical composition of essential oils of Mentha longifolia L. and cumin seed (dried seed of the herb Cuminum cyminum L.) and their antibacterial efficacy alone and combined with nisin on Bacillus cereus and Bacillus subtilis. Materials & Methods : The essential oil of the Mentha longifolia L. and Cuminum cyminum L. were obtained using steam distillation method by Clevenger apparatus and their chemical composition was assed by Gas chromatography-mass spectrometry (GC/MS). Broth microdilution susceptibility assay is used to determine minimum inhibitory concentration of essential oils and nisin. Results : Pulegone (31.54%) and Cumin aldehyde (29.02%) were the most abundant chemicals in horse-mint and cumin seed, respectively. Mentha longifolia , cumin , and nisin showed antibacterial activity on Bacillus cereus in concentration of 0.25%, 0.25%, and 10µg/ml, respectively. The corresponding activity on Bacillus subtilis were 0.25%, 0.125%, and 25µg/ml. Conclusion : The combined use of these essentials oils with nisin increased their antibacterial properties substantially. Furthermore, the bacterial growth curve showed that the efficacy of cumin seed alone or combined with nisin were greater to that of Mentha longifolia. The results of this study can be employed in food industry to overcome the hazards posed by pathogenic microorganisms. Source: Urmia Med J 2010: 21(4): 379 ISSN: 1027-3727
Mentha longifolia L.
Cuminum cyminum L.
Antibacterial
Nisin
2010
12
01
324
331
http://umj.umsu.ac.ir/article-1-785-en.pdf
32-786
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
EFFECT OF AEROBIC EXERCISE ON HORMONAL LEVEL AND LIPID PROFILE IN POLYCYSTIC OVARY SYNDROME WOMEN
Asghar
Tofighi
a.tofighi@urmia.ac.ir
Bakhtiar
Tartibian
Mir Hassan
Ameri
Soheila
Najafi Eliasabad
Arezoo
Asemi
Ali
Shargh
Received: 15 Sep, 2010 Accepted: 2 Nov, 2010 Abstract Background & Aims : Polycystic Ovary Syndrome (POS) is a common endocrine disorder in women in which an ovulation problem is often the cause of infertility . The purpose of this study was to evaluate the effects of aerobic exercise on POS abnormalities in young women. Materials & Methods : Thirty POS women were randomly divided into experimental and control groups. The experimental group performed selective aerobic training for 10 weeks. The control group did not participate in any exercise program during the study period. Anthropometric variables and fasting blood samples were collected for assay of research variables before and after exercise regimen. Plasma LH and FSH were analyzed by radioimmunoassay method. Testosterone and insulin were measured with Electrochemiluminesence (ECL) technique. SHBG concentration was also detected by Immuneradioimetricassay (IRMA). Results : Data analysis showed that aerobic training decreased significantly WHR, fat percentage, LH level, LH/FSH proportion, SHBG, and serum insulin levels in the experimental group (P<0.05). Also T student test analysis showed that there were significant differences between experimental and control group in mean LH level, LH/FSH proportion, SHBG and serum insulin level (P<0.05). Conclusion : The results of this research showed positive effects of aerobic exercise on hormonal levels and lipid profiles of women with POS. Source: Urmia Med J 2010: 21(4): 378 ISSN: 1027-3727
Keywords : Aerobic exercise
LH/FSH
SHBG
T estosterone
Insulin
POS
2010
12
01
332
338
http://umj.umsu.ac.ir/article-1-786-en.pdf
32-787
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
THE PREVALENCE OF GENETIC DISORDERS IN EAST AZERBAIJAN PROVINCE
Saeed
Dastgiri
saeed.dastgiri@gmail.com
Mortaza
Bonyadi
Tooba
Mizani
Inborn Genetic Diseases
Prevalence
Epidemiology
2010
12
01
339
346
http://umj.umsu.ac.ir/article-1-787-en.pdf
32-788
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
QUALITY GAP IN PRIMARY HEALTH CARE IN URMIA HEALTH CARE CENTERS, 2009
Ali
Gholami
Shaker
Salarilak
Rasool
Gharaaghaji
r-gharaaghaji@umsu.ac.ir
Ali
Sadaghiyanifar
Leila
Moosavi Jahromi
Received: 25 Aug, 2010 Accepted: 23 Oct, 2010 Abstract Background ;Aims : According to modern approaches to management, satisfactory quality must meet consumer’s requests . One of the first basic steps in improvement quality is recognizing consumers' perceptions and expectation. The aim of this study was to determine the quality gap in primary health care services in Urmia health care centers following consumers' perceptions and expectations. Materials & Methods: This analytic-descriptive study (cross-sectional) covered 400 females that referred to Urmia health care centers the study population was selected with systematic random method. Data were gathered using a research questionnaire. Results : It was indicated that there was a quality gap in all dimensions. Overall quality gap is (-0.61) and the largest gap was in reliability dimension (-0.78) and the smallest gap was observed in tangibility dimension (-0.23). There was no significant relation between age and education level of consumers with quality gap (P>0.05). Conclusion : The results of this study show that there is a negative gap in most quality dimensions of Urmia health system and consumers' expectations are not granted. Source: Urmia Med J 2010: 21(4):376 ISSN: 1027-3727
Quality gap
Primary health care
Health centers
Urmia
2010
12
01
347
353
http://umj.umsu.ac.ir/article-1-788-en.pdf
32-789
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
A COMPARISON OF FAMILY FUNCTIONING IN OBSESSIVE COMPULSIVE DISORDER PATIENTS WITH HEALTHY SUBJECTS
Hossein
Gholizadeh
Mansoor
Bayrami
E-mail: hossein.gholizade@yahoo.com
Alireza
Farnam
Mehdi
Imani
Jaber
Pirzade
Family functioning
Obsessive compulsive disorder
McMaster model
2010
12
01
354
360
http://umj.umsu.ac.ir/article-1-789-en.pdf
32-790
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
EVALUATION OF THE EFFECT OF SANYNJIAO ACUPRESSURE ON THE PROCESS OF ACTIVE PHASE OF LABOR IN PRIMIPARAS
Maryam
Kashanian
maryamkashanian@yahoo.com
Shadab
Shah Ali
Shohre
Bahasadri
Received: 27 July, 2010 Accepted: 7 Sep, 2010 Abstract Background & Aims : The purpose of the present study is to evaluate the effect of acupressure at the Sanyinjiao point (SP6) on the duration and pain of the active phase of labor in n ulliparas women. Materials & Methods : A single blind randomized clinical trial was performed on 120 eligible n ulliparas who were at the beginning of active phase of labor. The women were randomly assigned into two groups. The case group (n=60), received acupressure at Sanyinjiao point,(above the ankle), for 30 minutes during contractions. In the control group (n=60), simply a touch at this point without massage was performed. Two hours later a second pelvic examination was performed and in the absence of good forceful contractions oxytocin in the classical form was infused. Finally, the duration of active phase, severity of pain (using the Visual Analogue Scale, VAS), the amount of necessary oxytocin, and necessity to administer oxytocin, and the route of delivery were compared between both groups and statistical analysis was performed using SPSS 15. Results : The mean duration of active phase was shorter in the case group (252.37±108.50 min vs 441.38 ± 155.88, P=0.0001). Six patients (10%) in the case group and 25 women (41.7%) in the control group delivered via cesarean section (P=0.0001). The severity of pain in the case group was less than the control group (5.87± 1.77 vs 6.79 ±1.52, P=0.003). Twenty five women (41.7%) in the case group and 38 women (63.3%) in the control group needed oxytocin (P=0.017), the amount of necessary oxytocin in the case group was less than the control group (73.33± 97.19 ml vs 126.6± 97.19 ml, P= 0.003). Conclusion : Acupressure at Sanyinjiao point (SP6) reduced the duration and severity of pain of the active phase of labor, cesarean section rates and necessity and amount of oxytocin. Source: Urmia Med J 2010: 21(4): 374 ISSN: 1027-3727
Acupressure at Sanyinjiao point (SP6)
Active phase of labor
Delivery
Pain
Oxytocin Cesarean section
2010
12
01
361
367
http://umj.umsu.ac.ir/article-1-790-en.pdf
32-791
2024-03-29
10.1002
Studies in Medical Sciences
Studies in Medical Sciences
2717-008X
2717-008X
10.61186/umj
2010
21
4
ACUTE SCROTUM SECONDARY TO TICK-BITE
sepehrhamedanchi@yahoo.com
Received: 7 Sep, 2010 Accepted: 1 Nov, 2010 Abstract Acute scrotal pain is a unique emergency in urological field and necessitates a quick intervention because the most probability in this situation is teticular torsion which in case of delay can lead to irreversible testicular damage. The patient is a 24 year old man who complained of sudden left teticular pain from 4 hours ago. Severity of pain had woken him during the night. In history and physical examination the primary findings were inconclusive and the diagnosis of torsion could not be ruled out. Paraclinic study began but in Doppler ultrasonography testicular blood flow was normal. In secondary assessment we noticed a gray small papule in the posterior aspect of left hemiscrotum and then we extracted the lesion from scrotal wall. It was a thick, sucking blood, penetrated scrotum to half of his body length, so the symptoms resolved. We reported this case to underline the importance of quick management of acute scrotum in association with paying attention to meticulous history taking and physical examination even in case of emergency. Source: Urmia Med J 2010: 21(4): 373 ISSN: 1027-3727
Acute scrotum
Testicular torsion
Insect/tick bite
2010
12
01
368
372
http://umj.umsu.ac.ir/article-1-791-en.pdf