fa بررسی مشخصات دموگرافیک و بالینی بیماران مبتلا به سرطان پستان در ارومیه، روش غربالگری مناسب کدام می تواند باشد؟ آناتومی آناتومی پژوهشي(توصیفی- تحلیلی) Research <p class="Pazeresh" dir="rtl" style="MARGIN: 0in 0in 0pt TEXT-ALIGN: center" align="center"><span lang="FA" style="FONT-FAMILY: "B Lotus""><font size="3"><strong>تاریخ دریافت 12/12/88، تاریخ پذیرش 29/2/89<p></p></strong></font></span></p><p class="Pazeresh" dir="rtl" style="MARGIN: 0in 0in 0pt TEXT-ALIGN: center" align="center"><span lang="FA" style="FONT-FAMILY: "B Lotus""><p><font size="3"><strong> </strong></font></p></span></p><p class="Titrmatn" dir="rtl" style="MARGIN: 0in 0in 0pt LINE-HEIGHT: 17pt TEXT-ALIGN: center mso-line-height-rule: exactly mso-outline-level: 1" align="center"><strong><font size="3"><font face="Times New Roman"><span lang="FA" style="FONT-FAMILY: Yagut mso-ascii-font-family: Calibri mso-hansi-font-family: Calibri mso-no-proof: yes">چکیده</span><span dir="ltr" style="FONT-FAMILY: "Calibri","sans-serif" mso-no-proof: yes"><p></p></span></font></font></strong></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt"><font face="Times New Roman"><span><strong>پیش زمینه</strong></span><span lang="AR-SA" dir="ltr" style="mso-bidi-font-weight: bold"><span dir="ltr"></span><font size="2"> </font></span><b style="mso-ansi-font-weight: normal"><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">و هدف</span></b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">: سرطان پستان، بعد از<span style="COLOR: red"><font size="2"> </font></span>پوست، شایع‌ترین سرطان خانم­ها است </span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">و</span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt"> راه پیشگیری قطعی ندارد</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">.تشخیص زود رس،با ماموگرافی،انتخاب روش</span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">­ها</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">ی درمانی، موفقیت درمان و طول عمر را زیاد </span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">می­</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">کند.</span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt"> سرطان پستان در ایران سومین سرطان شایع به شمار می‌رود. هدف این مطالعه بررسی و تعیین مرحله بیماری و سن بیماران در موقع مراجعه می­باشد.<p></p></span></font></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt"><font face="Times New Roman"><b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">مواد و روش کار</span></b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">:</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt"> مشخصات بیمارانی که با سرطان پستان به درمانگاه خون وانکولوژی مراجعه داشتند، براساس پرسش­نامه­ی تنظیمی از پرونده، پرسش مستقیم از بیماران مراجعه کننده برای پیگیری و یا پرسش تلفنی جمع آوری و آنالیز شد.<p></p></span></font></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt"><font face="Times New Roman"><b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">یافته­ها</span></b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">: در این مطالعه 118 بیمار، 3مرد و</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt"> 115 زن در محدوده سنی 21تا 76سال، با میانگین سنی 49/49 و میانه سنی 48 سال بررسی شدند. بیشترین بیماران (35درصد) در گروه سنی 40تا49 بودند. 21درصد مرحله پیشرفته بیماری، 5/47درصد گرفتاری </span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">لنفندها</span></font><font face="Times New Roman"><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">ی زیر بغل، 11درصد عدم گرفتاری <br></span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">لنفندها</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">ی زیر بغل و20درصد وضعیت نامشخص گرفتاری </span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">لنفند­ها</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">ی زیر بغل داشتند.</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt"> </span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">سن شروع قاعدگی در 28درصد موارد زیر14، در90درصد زیر16 و در 10درصد بالای16سال بود. اولین زایمان­های ترم 100درصد موارد زیر 35 سال، 95درصد زیر 30سال، 81درصد زیر 25 سال و 43درصد زیر20سال رخ داده است. 9درصد از بیماران خانم زایمان نکرده اند. هشت بیمار (77/6درصد) سابقه فامیلی سرطان پستان داشتند.<p></p></span></font></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt"><font face="Times New Roman"><b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">بحث و نتیجه گیری</span></b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt">: این مطالعه نشان می­دهد در این منطقه تشخیص و درمان سرطان پستان در سنین پایین و در مراحل پیشرفته صورت می­گیرد. به نظر می­رسد افزایش آگاهی خانم­ها و ایجاد تسهیلات برای تشخیص زودتر بیماری به­خصوص با روش معاینه بالینی</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt"> دوره­ای</span><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt"> پستان نیاز هست.</span><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><p></p></span></font></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt TEXT-ALIGN: center" align="center"><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt"><p><font face="Times New Roman"> </font></p></span></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt TEXT-ALIGN: center mso-outline-level: 1" align="center"><font face="Times New Roman"><b><span lang="AR-SA" style="FONT-SIZE: 10pt FONT-FAMILY: Lotus">مجله پزشکی ارومیه، دوره بیست و یکم، شماره‌ سوم، ص 277-273، پاییز 1389</span></b><span lang="AR-SA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-ansi-font-size: 8.5pt"><p></p></span></font></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt TEXT-ALIGN: center" align="center"><span lang="AR-SA" style="FONT-FAMILY: Nazanin mso-bidi-font-size: 8.5pt"><p><font face="Times New Roman" size="2"> </font></p></span></p><p class="Chekide" dir="rtl" style="MARGIN: 0in 0in 0pt"><font face="Times New Roman"><b><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">آدرس مکاتبه</span></b><span lang="FA" style="FONT-SIZE: 9.5pt FONT-FAMILY: Nazanin mso-bidi-language: FA mso-ansi-font-size: 8.5pt">: ارومیه، مرکز آموزشی و درمانی امام خمینی ارومیه، بخش خون و انکولوژی، تلفن تماس: 09144431632<p></p></span></font></p><span style="FONT-SIZE: 12pt FONT-FAMILY: "Times New Roman","serif" mso-fareast-font-family: 'Times New Roman' mso-bidi-language: AR-SA mso-ansi-language: EN-US mso-fareast-language: EN-US">Email: Davood.maleki@gmail.com</span> <p class="Anevesandegan" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: center" align="center"><strong><span style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: "Times New Roman","serif"">Received: 3 March, 2010 Accepted: 19 May, 2010</span><span style="FONT-SIZE: 10pt FONT-STYLE: normal FONT-FAMILY: "Times New Roman","serif" mso-bidi-font-family: Arial"> <p></p></span></strong></p><p class="Abstract" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><span style="FONT-SIZE: 12pt FONT-FAMILY: "Times New Roman","serif" mso-fareast-font-family: Times-Roman"><strong>Abstract<span lang="FA" dir="rtl"><p></p></span></strong></span></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><font size="3"><i><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><strong>Background &Aims</strong></span></i><span><strong>:</strong> Breast cancer after skin cancer is the most common type of cancer in women and is not preventable, but early detection</span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif" mso-fareast-font-family: KeplerStd-Regular"> through mammography</span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""> improves treatment options, success,</span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif" mso-fareast-font-family: KeplerStd-Regular"> and survival.</span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""> Breast cancer is </span><span style="FONT-FAMILY: "Times New Roman","serif" mso-ansi-language: EN-US">the </span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">third most common malignant neoplasm in Iran (10% of all cancers). </span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif" mso-fareast-font-family: KeplerStd-Regular">The aim of this study was to determine the age of patients and the stage of breast cancer at the time of diagnosis.<p></p></span></font></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><font size="3"><b><i><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">Materials & Methods</span></i></b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">: This study examined the demographic characteristics and clinical presentation of all cases in the Hematology and Oncology Clinic of Imam hospital in Urmia. A questionnaire was used to collect data from patients' medical files and phone call contact and then analyzed. <p></p></span></font></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><font size="3"><b><i><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">Results</span></i></b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">: There were 118 patients, three men and 115 women (21-76 years of age). The mean and median ages at diagnosis were 49.49 and 48 years of age, respectively. Most of </span><span style="FONT-FAMILY: "Times New Roman","serif" mso-ansi-language: EN-US">the </span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">patients (35.5%) were diagnosed between 40 and 49 years of age. There were 21% locally advanced or metastatic 47.5% axillary lymph node involvement, 11% no axillary lymph node involvement and 20% unknown axillary lymph nodes status. First menstruation has been occurred in 90% under age 16 yr and in 28% before age 14. First full term pregnancy of 100% was before age 35, 95% before age 30 and 81% before age 25 and 9%</span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif" mso-ansi-language: EN-US"> </span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">have had no pregnancy. 6.77% had family history of breast cancer. <p></p></span></font></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><font size="3"><b><i><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">Conclusion:</span></i></b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""> In this region, breast cancer is diagnosed in earlier years of age and advanced stages. <p></p></span></font></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><font size="3">It is necessary to increase public awareness about breast cancer by women, and facilitate early detection of diseases especially by periodic clinical breast examinations. <p></p></font></span></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><p><font size="3"> </font></p></span></b><font size="3"><b><i><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">Address</span></i></b><b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">:</span></b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""> Hematology</span><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif" mso-ansi-language: EN-US"> </span></font><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><font size="3">& Oncology<b> </b>Ward<b>, </b>Imam Hospital, Urmia, Iran<font face="Times New Roman"><span style="mso-spacerun: yes">   </span><b>Tel</b></font></font><font size="3">: (+98) 9144431632<p></p></font></span></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><p><font size="3"> </font></p></span></b><font size="3"><b><i><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">Email</span></i></b><b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">:</span></b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif"">davood.maleki@gmail.com<p></p></span></font></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: justify"><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><p><font size="3"> </font></p></span></p><p class="Amatnmagale" style="MARGIN: 0in 0in 0pt DIRECTION: ltr LINE-HEIGHT: normal unicode-bidi: embed TEXT-ALIGN: center" align="center"><b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><font size="3">Source:</font></span></b><span lang="X-NONE" style="FONT-FAMILY: "Times New Roman","serif""><font size="3"> Urmia Med J 2010: 21(3): 273</font><font size="3"> ISSN: 1027-3727<p></p></font></span></p><p></p> سرطان پستان، مرد، غربالگری Breast cancer, Men, Screening 273 277 http://umj.umsu.ac.ir/browse.php?a_code=A-10-3-135&slc_lang=fa&sid=1 Davood Maleki داود ملکی Davood.maleki@gmail.com 370031947532846002540 370031947532846002540 Yes