en پاتولوژی پاتولوژی پژوهشي(توصیفی- تحلیلی) Research &nbsp; <br> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><strong>Background and Objective:</strong> Celiac disease is an immune-mediated enteropathy characterized by gluten-induced intestinal mucosal damage that induces immune destruction in genetically susceptible individuals. Among its important and relatively common complications are hematologic disorders. This study statistically evaluated the frequency of hematologic abnormalities in children with celiac disease.</span></span><br> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><strong>Materials and Methods:</strong> In this descriptive cross-sectional study, all children under 16 years of age hospitalized at Shahid Motahari Hospital in Urmia from 2019 to 2021 with biopsy-proven celiac disease according to the Marsh classification were included. The collected data included age, sex, WBC count, hemoglobin level, platelet count, prothrombin time, partial thromboplastin time, and international normalized ratio. All analyses were performed using SPSS version 27.</span></span><br> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><strong>Results:</strong> Among the 67 patients enrolled in the study, 6% had leukocytosis, 11.9% had leukopenia, 10.5% had anemia, 9% had thrombocytosis, and 1.5% had thrombocytopenia. Prothrombin time abnormality was observed in 13.5% of patients, and partial thromboplastin time abnormality in 17.9%. Coagulation disorders were more frequent in girls with celiac disease (p < 0.05).</span></span><br> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><strong>Conclusion:</strong> The most common hematologic abnormality in children with celiac disease was coagulation disorders. A significant association was found between sex and coagulation abnormalities, with girls showing a higher frequency of these disorders.</span></span> Celiac disease, Children, Hematologic disorders, Urmia 231 237 http://umj.umsu.ac.ir/browse.php?a_code=A-10-4367-8&slc_lang=en&sid=1 Farzaneh Javanmard javanmard.f@umsu.ac.ir 3700319475328460038483 3700319475328460038483 Yes Department of pathology,Faculty of medicine , Urmia university of medical science , Urmia,Iran Saman Rahimi serajgah samanrahimi19@gmail.com 3700319475328460038484 3700319475328460038484 No Faculty of medicine,Urmia Univercity of medical science , Urmia, Iran.