fa بررسی هزینه اثربخشی واکسیناسیون دام برعلیه بروسلوز در استان آذربایجان‌غربی آناتومی آناتومی پژوهشي(توصیفی- تحلیلی) Research <p> <strong>Received: 13 January, 2009 Accepted: 4 Feb, 2009</strong></p><p>  <strong>Abstract</strong> </p><p> <i> <strong>Background & Aims</strong> </i>: Brucellosis is a widespread, economically devastating and highly infectious zoonosis. Mass immunization has become a favorite strategy to control of disease .in, this study, we tried to estimate marginal effectiveness of livestock immunization program in West-Azerbayjan province. </p><p> <strong><i> Materials &Methods </i></strong>: Epidemiological data about of brucellosis was gathered through literature review, expert opinion, existing resources of data and synthesis by modeling of other data and transmission of disease pattern. In a state transition model different stages of disease and intervention in three scenario (cover of immunization with 50%, 80% and 0%)were simulated and estimate the economic benefit and cost –effectiveness through the control of brucellosis by mass vaccination of livestock. </p><p> <strong><i> Results </i></strong>: In a scenario of cover with 50% reduction of brucellosis transmission between animals achieved to vaccination , estimated intervention costs were 102270000000R(Iranian Rials) & the overall disease cost reduction due intervention was 269124000000 R (Iranian Rials) and benefit-cost ratio is 322%. In a scenario of cover with 80%, estimated intervention costs were 163710000000R (Iranian Rials) & the overall disease cost reduction due intervention was 322125000000 R (Iranian Rials). </p><p> <strong><i> Conclusion </i></strong>: Our study showed that effectiveness of immunization against brucellosis is quite significant. Calculation using basic estimates of cost of intervention program implies that this intervention is possibly very cost-effective and if with other interventions, such as control and limitation of livestock mobility, the eradication of disease is available aims. </p><p>  </p><p> <strong><i> Keywords: </i></strong>Brucellosis, Immunization, Cost Effctiveness, Modelling, Livestock </p><p>  </p><p> <strong><i> Address: </i></strong>Public Health Department, Health School, Nazlou Rade, Urmia, Iran, <strong>Tel:</strong> (+98441)2770047 </p><p>  </p><p> <strong><i> E-mail </i></strong>: <a href="mailto:rsljvd@yahoo.com">rsljvd@yahoo.com </a></p><p>  </p><p> <strong> Source </strong>: UMJ 2009: 20(1): 077 ISSN: 1027-3727 </p><br clear="all" > بروسلوز، ایمن سازی، اثر بخشی، تحلیل هزینه - اثربخشی Brucellosis, Immunization, Cost Effctiveness, Modelling, Livestock 13 20 http://umj.umsu.ac.ir/browse.php?a_code=A-10-3-52&slc_lang=fa&sid=1 Rasouli J , MSC جواد رسولی 370031947532846001411 370031947532846001411 Yes Holakoui K , PhD دکتر کوروش هلاکویی‌نائینی 370031947532846001412 370031947532846001412 No Forouzanfar MH , PhD دکتر محمد حسین فروزانفر 370031947532846001413 370031947532846001413 No Salari S , PhD دکتر شاکر سالاری‌لک 370031947532846001414 370031947532846001414 No Bahoner , PhD دکتر محمدباهنر 370031947532846001415 370031947532846001415 No Rashidian A , دکتر آرش رشیدیان 370031947532846001416 370031947532846001416 No