fa مقایسه نسبت Spo2/Fio2 با نسبت Pao2/Fio2 در بیماران مبتلا به آسیب حاد ریه و سندرم دیسترس حاد تنفسی آناتومی آناتومی پژوهشي(توصیفی- تحلیلی) Research <p class="Chekide" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0% MARGIN: 0cm 0cm 0pt unicode-bidi: embed DIRECTION: rtl" dir="rtl"><b><span lang="AR-SA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-ansi-font-size: 8.5pt">پیش‌زمینه و هدف:</span></b><span lang="AR-SA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-ansi-font-size: 8.5pt"> </span><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt">کرایتریاهای تشخیصی </span><font size="2"><font face="Times New Roman"><span dir="ltr">ALI</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> و </span><font size="2"><font face="Times New Roman"><span dir="ltr">ARDS</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> شامل شروع حاد بیماری، یافته‌های رادیوگرافی سینه مطابق با انفیلتراسیون دوطرفه ریه و نبود اختلال عملکرد بطن چپ و نسبت (</span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span>) </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Pao₂/Fio₂</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font face="Nazanin" size="2">کمتر یا مساوی 200 برای </font></span></span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">ARDS</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> و کمتر یا مساوی 300 برای </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">ALI</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span>؛ که مورد اخیر نیازمند نمونه‌گیری تهاجمی خون شریانی هست. </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Spo2</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> که توسط دستگاه پالس اکسی‌متری اندازه‌گیری می‌شود و محاسبه نسبت </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-font-family: 'Times New Roman'" dir="ltr">Spo₂/Fio₂</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font face="Nazanin" size="2">(</font></span></span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span>) را شاید بتوان یک آلترناتیو غیرتهاجمی جایگزین برای نسبت </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> در نظر گرفت.<p></p></span></p><p class="Chekide" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0% MARGIN: 0cm 0cm 0pt unicode-bidi: embed DIRECTION: rtl" dir="rtl"><b><span lang="AR-SA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-ansi-font-size: 8.5pt">مواد و روش کار:</span></b><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"> در یک مطالعه تحلیلی مقطعی، 70 بیمار مبتلا به </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">ALI</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> و </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">ARDS</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> بستری در </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">PICU</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> بیمارستان کودکان تبریز وارد مطالعه شدند. </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Spo₂</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font face="Nazanin" size="2">و </font></span></span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Pao₂</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font face="Nazanin" size="2">و </font></span></span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">Fio₂</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font face="Nazanin" size="2">در حداکثر بازه زمانی 5 دقیقه اندازه‌گیری شد و نسبت </font></span></span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> و </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> محاسبه شد و نسبت </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> با نسبت </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> مقایسه و ارتباط میان آن‌ها و حد آستانه نسبت </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> برای جایگزینی با نسبت </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> برای تشخیص </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">ARDS</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> و </span><font size="2"><font face="Times New Roman"><span style="mso-bidi-language: FA" dir="ltr">ALI</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> تعیین شد.<p></p></span></p><p class="Chekide" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0% MARGIN: 0cm 0cm 0pt unicode-bidi: embed DIRECTION: rtl" dir="rtl"><b><span lang="AR-SA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-ansi-font-size: 8.5pt">یافته‌ها</span></b><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt">: در مطالعه انجام‌شده رابطه نسبت </span><font size="2"><font face="Times New Roman"><span dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> با نسبت </span><font size="2"><font face="Times New Roman"><span dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> با معادله رگرسیون </span><font size="2"><font face="Times New Roman"><span dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> 61/0+57=</span><font size="2"><font face="Times New Roman"><span dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> محاسبه شد؛ و نسبت </span><font size="2"><font face="Times New Roman"><span dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> 181 و 235 مطابق با نسبت </span><font size="2"><font face="Times New Roman"><span dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span>200 و 300 بود. آستانه </span><font size="2"><font face="Times New Roman"><span dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> برای </span><font size="2"><font face="Times New Roman"><span dir="ltr">ALI</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> 235 بود که دارای 57 درصد حساسیت و 100 درصد اختصاصیت و آستانه</span><span lang="FA" style="FONT-FAMILY: "Tahoma","sans-serif" FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"> </span><font size="2"><font face="Times New Roman"><span dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> برای </span><font size="2"><font face="Times New Roman"><span dir="ltr">ARDS</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> 181 بود که دارای 71 درصد حساسیت و 82 درصد اختصاصیت بود؛ و جهت جایگزینی </span><font size="2"><font face="Times New Roman"><span dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> با </span><font size="2"><font face="Times New Roman"><span dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> 001/0</span><span dir="ltr"></span><span dir="ltr"></span><span dir="ltr"><span dir="ltr"></span><span dir="ltr"></span><font face="Times New Roman" size="2"><</font></span><span dir="rtl"></span><span dir="rtl"></span><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> </span><font size="2"><font face="Times New Roman"><span dir="ltr">P</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font size="2"><font face="Nazanin">هست.<p></p></font></font></span></span></p><p class="Chekide" style="TEXT-JUSTIFY: kashida TEXT-ALIGN: justify TEXT-KASHIDA: 0% MARGIN: 0cm 0cm 0pt unicode-bidi: embed DIRECTION: rtl" dir="rtl"><b><span lang="AR-SA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-ansi-font-size: 8.5pt">نتیجه‌گیری</span></b><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt">: نسبت </span><font size="2"><font face="Times New Roman"><span dir="ltr">SF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font face="Nazanin" size="2">که مارکر غیرتهاجمی قابل‌اعتماد جهت جایگزینی با نسبت </font></span></span><font size="2"><font face="Times New Roman"><span dir="ltr">PF</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> جهت تشخیص </span><font size="2"><font face="Times New Roman"><span dir="ltr">ALI</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span lang="FA" style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> و </span><font size="2"><font face="Times New Roman"><span dir="ltr">ARDS</span><span dir="rtl"></span><span dir="rtl"></span></font></font><span style="FONT-FAMILY: Nazanin FONT-SIZE: 9.5pt mso-bidi-language: FA mso-ansi-font-size: 8.5pt"><span dir="rtl"></span><span dir="rtl"></span> <span lang="FA"><font size="2"><font face="Nazanin">هست و می‌توان پالس اکسی متری را جایگزین خون‌گیری شریانی نمود.<p></p></font></font></span></span></p> <p style="DIRECTION: ltr"> <strong><i> Background & Aims: </i></strong>Diagnostic criteria for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) requires acute onset of disease, chest radiograph demonstrating bilateral pulmonary infiltrates, lack of significant left ventricular dysfunction and Pao₂/Fio₂ (PF) ratio 300 for ALI or 200 for ARDS. And the latter one requires invasive arterial sampling. Measurement spo₂ by pulse oxi metry and calculation spo₂/Fio₂ (SF) ratio may be a reliable non invasive alternative to the PF ratio. </p><p> <strong><i> Materials & Methods: </i></strong>In this cross sectional study, 70 patient diagnosed for ALI or ARDS admitted in Tabriz children’s hospital PICU were enrolled. Then spo2, Fio2, Pao2 charted within 5 minutes were measured and the ratio of SF and PF were calculated and compared. SF threshold the values were determined to replacement PF ratio for diagnose ARDS and ALI. </p><p> <strong><i> Results: </i></strong>The relationship between SF and PF ratio was described by the following regression equation SF=57+0/61PF (P<0/001). SF ratios of 181 and 235 corresponded of PF ratio 300 and 200. The ALI SF cutoff of 235 had 57% sensitivity and 100% specificity, and ARDS, SF cutoff of 181 had 71% sensitivity and 82% specificity. </p><p> <strong><i> Conclusion: </i></strong>SF ratio is a reliable noninvasive marker for PF ratio to identify children with ALI or ARDS. <strong>A </strong>nd can be replaced pulse oximetry by arterial blood sampling. </p><p>  </p><p> SOURCE: URMIA MED J 2014: 25(10): 909 ISSN: 1027-3727 </p><p>  </p> ARDS, ALI, Pao2/Fio2, پالس اکسی متری ARDS, ALI, Pao2/Fio2 , Pulse oximetry 0 0 http://umj.umsu.ac.ir/browse.php?a_code=A-10-582-544&slc_lang=fa&sid=1 Nemat Bilan نعمت بیلان dastranji61@gmail.com 3700319475328460010832 3700319475328460010832 Yes Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz بیمارستان کودکان تبریز مرکز تحقیقات سلامت کودکان، دانشگاه علوم پزشکی تبریز، Afshin Ghale Golab Behbahani افشین قلعه گلاب بهبهانی 3700319475328460010833 3700319475328460010833 No Children’s Hospital, Tabriz University of Medical Sciences بیمارستان کودکان تبریز، دانشگاه علوم پزشکی تبریز، Azar Dastranji آذر دسترنجی 3700319475328460010834 3700319475328460010834 No , Children’s Hospital, Tabriz University of Medical Sciences بیمارستان کودکان تبریز، دانشگاه علوم پزشکی تبریز،