TY - JOUR T1 - CAPTOPRIL-INDUCED ACUTE RENAL FAILURE IN BARTTER SYNDROME TT - گزارش یک مورد نارسایی حاد کلیه به دنبال مصرف کاپتوپریل در یک کودک مبتلا به سندرم بارتر JF - URMIAMJ JO - URMIAMJ VL - 19 IS - 1 UR - http://umj.umsu.ac.ir/article-1-265-en.html Y1 - 2008 SP - 86 EP - 89 KW - Bartter syndrome KW - Failure to thrive KW - Renal insufficiency KW - Captopril KW - GH KW - IGF N2 - Bartter syndrome presenting in neonatal or early infancy is characterized by salt loosing tubulopathy, hypokalemia, and metabolic alkalosis. Failure to thrive is one of the most common findings in neonatal bartter syndrome. Angiotensin converting enzyme inhibitors are one of the therapeutic options for improving growth in these patients.We describe a case of neonatal bartter syndrome with mild impairment of renal function for whom captopril started to promote better growth but she presented later with clinical and laboratory signs of exacerbation of renal impairment which were significantly resolved after discontinuing captopril.In patients with Bartter syndrome and underlying renal dysfunction angiotensin converting enzyme inhibitors should be used with caution and low dose M3 ER -