Abstract Background & Aims: Hexamethylene diisocyanate is an aliphatic isocyanate and car painters are exposed to it. One of the most important disorders is occupational asthma. The aim of this study was to survey the effect of 1, 6 hexamethylene diisocyanate on the peak expiratory flow test to car painters in Isfahan. Materials & Methods: In this descriptive and a cross-sectional study the forty three car painters were included. The sample were extracted and analyzed with high performance liquid chromatography. Peak expiratory flow test was carried out within a period of one week of working shift. Result: The averages of daily and weekly exposure of workers to Hexamethylene diisocyanate concentration were. 0.42±0.1 and 0.13±0.05mg/m3, respectively The average of variation percent of peak expiratory flow of workers on painting day were 11.2 % ±1.8 % and the change average of peak expiratory flow of worker on the post day painting were 7.9 %±1.9. 72% . 72% of the painters had a variation more than 10% of the peak expiratory flow on painting day. Conclusion: All inhalation exposure was 10% more than the threshold standard limits value (tenfold of TLV) Keywords: Hexamethylene diisocyante, Peak expiratory flow test, Isocyanat Address: Department of Occupational Health, Faculty of Health, Isfahan University of Medical Sciences Isfahan, Iran Tel: (+98) 9168424997 Email: a.barkhordari2007@gmail.com Source: Urmia Med J 2010: 21(1): 099 ISSN: 1027-3727

Keywords: Hexamethylene diisocyante, Peak expiratory flow test, Isocyanat

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