Volume 29, Issue 12 (March 2019)
Studies in Medical Sciences 2019, 29(12): 896-903 |
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ahmadi F, fallahmohammadi Z. THE EFFECT OF FOUR WEEKS' VOLUNTARY EXERCISE ON A REGULAR AND COMPLEX WHEEL RUNNING ON NG2 BRAIN LEVELS IN HEALTHY MALE WISTAR RATS. Studies in Medical Sciences 2019; 29 (12) :896-903
URL: http://umj.umsu.ac.ir/article-1-4534-en.html
URL: http://umj.umsu.ac.ir/article-1-4534-en.html
Associate Professor of Exercise Physiology, Department of Exercise Physiology, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Iran (Corresponding Author) , ziafalm@yahoo.com
Abstract: (2418 Views)
Background and objective: NGF-2 is oligodendrocyte progenitor cell which has neuroprotective functions. This study was designed to investigate and compare the effect of a 4-week voluntary training program on regular and complex running wheels on NGF-2 levels in healthy Wistar male rats.
Materials and methods: Thirty adult Wistar male rats were divided into 3 groups: voluntary training on regular running wheel, voluntary training on complex running wheel, and control. For measuring the NGF-2 levels in the brain, the ELISA test was used. One-way analysis of variance and Tuckey post-hoc tests were employed for comparing the intergroup differences. All the statistical analysis were conducted by SPSS software (version 20).
Results: Performing voluntary training programs on regular (p=0.03) and complex running wheels (p=0.001) resulted in significant changes in NGF-2 levels in the brain. There was also a significant difference between these two modes of training programs (p=0.05).
Conclusion: Based on the results, these 2 training protocols can be regarded as positive intervening factors for increasing oligodendrocytes in healthy rats, although the complex running wheel voluntary training has shown to be more promising.
Materials and methods: Thirty adult Wistar male rats were divided into 3 groups: voluntary training on regular running wheel, voluntary training on complex running wheel, and control. For measuring the NGF-2 levels in the brain, the ELISA test was used. One-way analysis of variance and Tuckey post-hoc tests were employed for comparing the intergroup differences. All the statistical analysis were conducted by SPSS software (version 20).
Results: Performing voluntary training programs on regular (p=0.03) and complex running wheels (p=0.001) resulted in significant changes in NGF-2 levels in the brain. There was also a significant difference between these two modes of training programs (p=0.05).
Conclusion: Based on the results, these 2 training protocols can be regarded as positive intervening factors for increasing oligodendrocytes in healthy rats, although the complex running wheel voluntary training has shown to be more promising.
Type of Study: Research |
Subject:
Exercise physiology
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