دوره 27، شماره 12 - ( ماهنامه اسفند 1395 )                   جلد 27 شماره 12 صفحات 1032-1040 | برگشت به فهرست نسخه ها
Urmia University ، j.tolouei@gmail.com
چکیده:   (1547 مشاهده)

Background & Aims: It is more important to know which of physical activities could be the most effective way to cause angiogenesis. In this regards, we have investigated an 8-week aerobic training on vascular endothelial growth factor (VEGF) and Endostatin (ES) in sedentary women.

Materials & Methods: 20 volunteer inactive women were chosen and were randomly divided in 2 groups of aerobic and control. Aerobic training programme consisted of 3 days per week for 8 weeks, each consists of 30 minutes with intensity of 65-70% of maximum heart rate was performed.. Before and after training, we have tested aerobic training and control group after an overnight fast. Blood Samples were used to conduct Enzyme-linked immunosorbent assay (ELISA). Independent and Dependent T-Test t were performed to see the significance level of (P<0.05.

Results: Statistical analysis revealed that aerobic training increased VEGF and decreased ES to a significant level. Consequently, the results of Independent T Test revealed that there is an obvious difference (P<0.05), between the amount of VEGF and ES in control and intervention group.

Conclusion:The results show that the equilibrium between angiogenesis and angiostatic agents. As a result, aerobic training is shifted toward angiogenesis factors. This result helps us to understand the process of angiogenesis consistence with aerobic training activities.

واژه‌های کلیدی: Aerobic training، Angiogenesis، VEGF، ES، Sedentary women
متن کامل [PDF 317 kb]   (640 دریافت)    
نوع مطالعه: کارآزمایی بالینی | موضوع مقاله: فیزیولوژی ورزشی
دریافت: ۱۳۹۵/۷/۶ | پذیرش: ۱۳۹۵/۸/۱۲ | انتشار: ۱۳۹۵/۱۲/۲۱