Volume 27, Number 12 (Monthly-Mar 2017) | J Urmia Univ Med Sci 2017, 27(12): 1032-1040 | Back to browse issues page



DOI: 10.18869/acadpub.umj.27.12.1032

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Tolouei Azar J, Ravasi A, Soori R, Akbarnejad A, Hemati Nafar M. The Effect of 8 Weeks Aerobic Training on Angiogenesis (VEGF) and Angiostatic (ES) Factors In Sedentary Women. J Urmia Univ Med Sci. 2017; 27 (12) :1032-1040
URL: http://umj.umsu.ac.ir/article-1-3608-en.html

Assistant Professor Urmia University , j.tolouei@gmail.com
Abstract:   (756 Views)

Background & Aims: It is more important to know which of physical activities could be the most effective way to cause angiogenesis. In this regards, we have investigated an 8-week aerobic training on vascular endothelial growth factor (VEGF) and Endostatin (ES) in sedentary women.

Materials & Methods: 20 volunteer inactive women were chosen and were randomly divided in 2 groups of aerobic and control. Aerobic training programme consisted of 3 days per week for 8 weeks, each consists of 30 minutes with intensity of 65-70% of maximum heart rate was performed.. Before and after training, we have tested aerobic training and control group after an overnight fast. Blood Samples were used to conduct Enzyme-linked immunosorbent assay (ELISA). Independent and Dependent T-Test t were performed to see the significance level of (P<0.05.

Results: Statistical analysis revealed that aerobic training increased VEGF and decreased ES to a significant level. Consequently, the results of Independent T Test revealed that there is an obvious difference (P<0.05), between the amount of VEGF and ES in control and intervention group.

Conclusion:The results show that the equilibrium between angiogenesis and angiostatic agents. As a result, aerobic training is shifted toward angiogenesis factors. This result helps us to understand the process of angiogenesis consistence with aerobic training activities.

Full-Text [PDF 317 kb]   (408 Downloads)    
Type of Study: Clinical trials | Subject: Exercise physiology
Received: 2016/09/27 | Accepted: 2016/11/2 | Published: 2017/03/11

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