Volume 19, Issue 3 (fall 2008)                   J Urmia Univ Med Sci 2008, 19(3): 271-274 | Back to browse issues page

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A REPORT OF TWO CASES WITH HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-1 ASSOCIATED WITH ADULT T-CELL LEUKEMIA/LYMPHOMA (ATLL) IN WEST AZERBAIJAN. J Urmia Univ Med Sci. 2008; 19 (3) :271-274
URL: http://umj.umsu.ac.ir/article-1-339-en.html
Abstract:   (19375 Views)

  D Maleki [1] , MD S Hejazy [2] , MD M Karamyar [3] , MD

 

 Received: 22 April, 2007 Accepted: 2 June, 2008

 Abstract

 Adult T-cell leukemia/lymphoma (ATLL) is a lymph proliferative neoplasm caused by human T-lymph tropic virus type 1 (HTLV-1), which is also the etiologic agentof HTLV-1-associated with myelopathy or tropical spastic para paresis.HTLV-1 is distributed worldwide, but is endemic onlyin certain parts of the world such as southwestern Japan, theCaribbean, Africa, parts of South America and Khorasan, the northeasternprovince of Iran.

 We describe two patients, one male and one female, respectively 45 and 53 years old and born in Urmia with clinical, laboratory, and morphologic finding characteristics of ATLL, and anti-HTLV-1 positive serums. Both diagnosed and treated as ATLL by chemotherapy and expired 9 months after the diagnosis.

 Our findings confirm the presence of HTLV-1 in West Azerbaijan . With respect to that, there is no defined treatment for HTLV-1 infection and its complications, so studies to determine the prevalence rates may be necessary in establishing prophylacticmeasures to reduce the rates of viral transmission.

 

  Keywords: Human T-lymph tropic virus type 1, Adult T-cell leukemia/lymphoma, Endemic

 

  Address : Imam Khomeini Hospital, Urmia, Iran Tel: 09144431632

 

 E-mail: davood.maleki@gmail.com

 

  Source: UMJ 2008: 19( 3 ): 288 ISSN: 1027-3727



  [1] Assistant Professor of Internal Disease, Urmia University of Medical Sciences (Corresponding Author)

  [2] Assistant Professor of Pediatric Disease, Urmia University of Medical Sciences

  [3] Assistant Professor of Pediatric Disease, Urmia University of Medical Sciences

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Type of Study: case report | Subject: آناتومی

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