Volume 24, Number 5 (Monthly August 2013)                   J Urmia Univ Med Sci 2013, 24(5): 329-338 | Back to browse issues page


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Ilkhanizadeh B, Nahali Moghaddam A, Hajishafiha M, Sadaghiani M, Nanbakhsh F, Deldar Y, et al . CORRELATION BETWEEN EMBRYO IMPLANTION AND FOLLICULAR FLUID SELECTED CYTOKINES AND HORMONE LEVELS IN WOMEN UNDER TREATMENT BY MICROINJECTION TECHNIQUE. J Urmia Univ Med Sci. 2013; 24 (5) :329-338
URL: http://umj.umsu.ac.ir/article-1-1770-en.html

Associate Professor of Pathology ,Reproductive Health Research Center, Urmia University of Medical Sciences, Urmia, Iran
Abstract:   (6829 Views)
 

Received: 23 Apr , 2013 Accepted: 28 Jun , 2013

 Abstract 

Background & Aims: Concentrations of certain substances in follicular fluid (FF) may related to fertilization outcome. The study aim was to identify FF markers with which to predict embryo implantation potential.

 

Materials & Methods: Concentrations of selected hormones, cytokines and growth factors in FF samples obtained during assisted reproduction treatment, Intracytoplasmic Sperm Injection (ICSI) method were related with treatment outcomes.

 

Results: Mean concentrations of 17beta-estradiol (E2), prolactin (PRL) and insulin-like growth factor (IGF)-I were significantly higher, in treatment attempts leading to a clinical pregnancy as compared with those in which no pregnancy was established. LH, growth hormone (GH), progesterone, and interleukin-1 (IL-1) concentrations are similar in successful and unsuccessful attempts.

 

Conclusions: Fertilization outcomes were related to FF levels of PRL, E2 and IGF-I. But LH, growth GH, progesterone, and IL-1 are not markers of success.

 
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Type of Study: Research | Subject: آناتومی
Received: 2013/08/6 | Accepted: 2013/08/12 | Published: 2013/08/12

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