Volume 24, Number 2 (Monthly 2013)                   J Urmia Univ Med Sci 2013, 24(2): 133-145 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rahimi B, Gharabaghi N, Hesari Z, Balanji S, Alinia T. PREVALENCE OF POTENTIAL DRUG INTERACTIONS IN PATIENTS IN THE INTENSIVE CARE UNIT OF URMIA TALEGHANI HOSPITAL. J Urmia Univ Med Sci. 2013; 24 (2) :133-145
URL: http://umj.umsu.ac.ir/article-1-1643-en.html

Assistant Professor of Medical Informatics , Urmia University of Medical Sciences , gharabaghi@umsu.ac.ir
Abstract:   (5631 Views)

 

Background & Aims: Potential Drug Interaction (PDI) is one of the medicine error which can led to undesirable reactions in patients. PDI occures when effect of toxocity of one medicine is affected by another one. This study aims to examination of of PDI freguency, clinical value ranking and risk factors in ICU ward of Urmia Taleghani hospital, Iran in 2011.

Materials & Methods: A cross-sectional study was carried out amog 193 inpatient of ICU ward. Data were collected retrospectively. Descriptive-analytical methods was used to analyse data including mean, median,  standard deviation and t-test. Data were anlysed by SPSS.

Results: Frequency of PDI was 73.6% and mean of PDI was 4.07. The most common PDI was Ranitidin + Midozolam with 26 (4.1%) of cases. grade of PDI was mild for 46 (7.9%), moderate for 192 (33%), sever for 51(8.8%), contradicted for 150 (25.8%), (), and unknown for 143 (24.4%). PDI effects manifested immediately for 195 (33.5%) and with delay for 384 (66.5%). 49.95 % of PDIs had significant clinical value and 41.19 % higly significant clinical value.

Conclusion: Knowledge of drug interaction, replacing of interacting drug with other drugs as much as possible, noticing of highly interacting drugs, deminishing number of prescribed drugs can reduce PDI number and its consequences.

 

SOURCE: URMIA MED J 2013: 24(2): 145 ISSN: 1027-3727

Full-Text [PDF 295 kb]   (1253 Downloads)    
Type of Study: Research | Subject: آناتومی
Received: 2013/05/12

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | URMIA MEDICAL JOURNAL

Designed & Developed by : Yektaweb