Abstract

  Background & Aims : Frozen section is a high- risk procedure with important consequences. As the histopathologic diagnosis of the frozen section may have serious consequences for the treatment of the patient, a high degree of accuracy is mandatory and quality control is important. The aim of this study was the evaluation of accuracy of frozen section by revision of slides in teaching hospitals of Urmia University of Medical Sciences including Imam Khomeini and Shahid Motahari hospitals.

  Methods & Materials : In this cross sectional study, the slides of all frozen section samples in teaching hospitals of Urmia University of Medical Sciences during 2003 to 2009 revised by two pathologists and compared with their final permanent section diagnoses.

  Results : A total of 155 neoplastic specimens in Imam Khomeini hospital and 83 neoplastic specimens in Shahid Motahari hospital were studied. Sensitivity, Specificity, positive and negative predictive values and accuracy in Iman Khomeini hospital were 95.6%, 100%, 100%, 96.5% and 96.7% and in Shahid Motahari hospital 100%, 98%, 96.2% , 100% and 98.9% , respectively. We had 8 discordant diagnoses, 3 cases (37.5%) were due to macroscopic discordance, 1 case (12.5%) of microscopic discordance and 5 cases (62.5%)of both macroscopic and microscopic discordance.

  Conclusion : As different studies showed accuracy of 91.5% to 97.4% for frozen section so we concluded that frozen sections are interpreted with acceptable accuracy in Urmia University Of Medical Sciences.

  SOURCE: URMIA MED J 2013: 24(1): 76 ISSN: 1027-3727